Sökning: "Enzyme Activation"

Visar resultat 21 - 25 av 397 avhandlingar innehållade orden Enzyme Activation.

  1. 21. Lipase and ω-Transaminase : Biocatalytic Investigations

    Författare :Maria Svedendahl; Per Berglund; Stefan Stefan Lutz; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; enzyme catalysis; enzyme catalytic promiscuity; molecular modeling; ω-transaminase; Biochemistry; Biokemi;

    Sammanfattning : In a lipase investigation, Candida antarctica lipase B (CALB) are explored for enzyme catalytic promiscuity. Enzyme catalytic promiscuity is shown by enzymes catalyzing alternative catalytic transformations proceeding via different transition state structures than normal. LÄS MER

  3. 22. Dynamic Covalent Resolution: Applications in System Screening and Asymmetric Synthesis

    Författare :Pornrapee Vongvilai; Olof Ramström; Benjamin Miller; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dynamic covalent kinetic combinatorial resolution; Self-screening; Transesterification; Amidation; Enzyme catalysis; Nitroaldol reaction; Secondary alcohols; Strecker reaction; Aminonitriles; Racemase; Enzyme catalytic promiscuity; Chemistry; Kemi; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi;

    Sammanfattning : Combined thermodynamic/kinetic events amount to a kinetically controlled Dynamic Combinatorial Resolution (DCR) process, where the lability of themolecules/aggregates are used to generate dynamics, and the species experiencing the lowest activation energy is selected via kinetic process. Bothinter- and intramolecular processes can be performed using this concept,resulting in complete resolution and associated amplification of the selected species. LÄS MER

  4. 23. Acute pancreatitis. With special reference to the activation peptide from carboxypeptidase B (CAPAP) as a predictor of severity

    Författare :Stefan Appelros; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; accuracy; exocrine dysfunction; radioimmunoassay; CAPAP; carboxypeptidase B; activation peptide; aetiology; prediction of severity; morbidity; mortality; severe acute pancreatitis; Incidence; acute pancreatitis; sensitivity; specificity; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : There is a wide range in the reported annual incidence of acute pancreatitis (AP). A minority of these patients develop a severe disease characterised by a high mortality and morbidity. In order to improve the outcome for patients with an attack of severe AP it is important to identify these patients early in the course of disease. LÄS MER

  5. 24. Serine Hydrolase Selectivity : Kinetics and applications in organic and analytical chemistry

    Författare :Anders Hamberg; Karl Hult; Dick Janssen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; monoacylation of diols; kinetic resolution; thermodynamics in enzyme catalysis; enzyme engineering; Biochemistry; Biokemi;

    Sammanfattning : The substrate selectivities for different serine hydrolases were utilized in various applications, presented in papers I-VI. The articles are discussed in the thesis in view of the kinetics of the enzyme catalysis involved. LÄS MER

  7. 25. Biosynthesis of capsaicinoids by recombinant Saccharomyces cerevisiae

    Författare :Nina Muratovska; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; capsaicinoids; nonivamide; baker’s yeast; Capsicum; Saccharomyces cerevisiae; Pseudomonas putida; lignin-derived substrates; vanillin aminotransaminase; reductive amination; vanillylamine; N-Acyltransferase; CoA-ligase; amide; whole-cell bioconversion; TRPV1 receptor; ion channel; calcium dye Fluo-4; flow cytometry;

    Sammanfattning : Throughout history, people have used products from different microorganisms and plants for many medicinal and nutritional applications. Chilli peppers have been used for spicing up food, but also for their pharmacological properties. LÄS MER