Sökning: "activation peptide"

Visar resultat 1 - 5 av 328 avhandlingar innehållade orden activation peptide.

  1. 1. Trypsinogen and Its Activation in Acute Pancreatitis

    Författare :Ulf Petersson; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TAP; ERCP; carboxypeptidase B activation peptide; trypsinogen activation peptide; trypsinogen activation; Acute pancreatitis; trypsinogen; CAPAP; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Pancreatic enzymes, neutrophils, free radicals and cytokines are involved in the pathophysiology of AP. Clarification of their interaction and time-course will improve our understanding of AP and provide a better basis for treatment. LÄS MER

  3. 2. Nitrates and Left Ventricular Dysfunction

    Författare :Erik Tingberg; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipid peroxidation; malondialdehyde; peptide; brain natriuretic peptide; left ventricular dysfunction; nitrates; acute myocardial infarction; heart failure; atrial natriuretic; diuretics; echocardiography; haemodynamic measurements; neurohumoral activation; diastolic dysfunction; Cardiovascular system; Medicin människa och djur ; Medicine human and vertebrates ; Kardiovaskulära systemet; oxidative stress; isoprostanes;

    Sammanfattning : Use of beta-blockers and inhibitors of the renin angiotensin system (RAS) is established practice in the treatment of chronic heart failure (CHF). Clinical studies also suggest beneficial long-term effects of nitrates in CHF. LÄS MER

  4. 3. Acute pancreatitis. With special reference to the activation peptide from carboxypeptidase B (CAPAP) as a predictor of severity

    Författare :Stefan Appelros; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; accuracy; exocrine dysfunction; radioimmunoassay; CAPAP; carboxypeptidase B; activation peptide; aetiology; prediction of severity; morbidity; mortality; severe acute pancreatitis; Incidence; acute pancreatitis; sensitivity; specificity; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : There is a wide range in the reported annual incidence of acute pancreatitis (AP). A minority of these patients develop a severe disease characterised by a high mortality and morbidity. In order to improve the outcome for patients with an attack of severe AP it is important to identify these patients early in the course of disease. LÄS MER

  5. 4. Activation of professional phagocytes with emphasis on the formyl peptide receptor family

    Författare :Jennie Karlsson; Göteborgs universitet; []
    Nyckelord :phagocyte; G-protein coupled receptor; chemoattractant; formyl peptide receptor; reactive oxygen species; calcium;

    Sammanfattning : Phagocytic cells such as neutrophil granulocytes and monocytes are an essential part of our innate immune system and play an important role in the battle against pathogens. G-protein coupled receptors (GPCRs) and more specifically chemoattractant receptors are a vital part in guiding phagocytes towards the site of infection. LÄS MER

  7. 5. Apoptosis Regulation via the Mitochondrial Pathway : Membrane Response upon Apoptotic Stimuli

    Författare :Marc-Antoine Sani; Gerhard Grobner; Antoinette Killian; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Apoptosis; BH4 peptide; Bax-α1 peptide; model membrane; cardiolipin; solid phase peptide synthesis; circular dichroism; solid-state nuclear magnetic resonance spectroscopy.; Biophysics; Biofysik;

    Sammanfattning : The aim of this thesis was the investigation of the mitochondrial response mechanisms upon apoptotic stimuli. The specific objectives were the biophysical characterization of membrane dynamics and the specific roles of lipids in the context of apoptotic regulation occurring at the mitochondrion and its complex membrane systems. LÄS MER