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Visar resultat 16 - 20 av 397 avhandlingar som matchar ovanstående sökkriterier.

1. 16. The influence of temperature on enzyme selectivity in organic media

   Författare :Åsa Jönsson; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; water activity; sub-zero temperatures; enantioselectivity; peptide yields; asymmetric reductions of ketones; peptide synthesis; ADH from Thermoanaerobium brockii; subtilisin; Enzyme catalysis; a-chymotrypsin; organic solvent; aqueous media; Biotechnology; Bioteknik;

   Sammanfattning : The influence of different reaction parameters on enzyme selectivity was investigated. The reaction conditions studied were solvent dependence, water activity and reaction temperature. LÄS MER

3. 17. Calculations of Reaction Mechanisms and Entropic Effects in Enzyme Catalysis

   Författare :Masoud Kazemi; Johan Åqvist; Per E. M. Siegbahn; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Enzyme catalysis; Entropy; Cytidine deamination; Ribosome; Peptidyl-tRNA hydrolysis; Peptide bond formation; Empirical valence bond method; Density functional theory; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biokemi; Biochemistry; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

   Sammanfattning : Ground state destabilization is a hypothesis to explain enzyme catalysis. The most popular interpretation of it is the entropic effect, which states that enzymes accelerate biochemical reactions by bringing the reactants to a favorable position and orientation and the entropy cost of this is compensated by enthalpy of binding. LÄS MER

4. 18. The development of a new combined adjuvant vector for mucosal immunization CTA1-DD/ISCOM

   Författare :Anja Helgeby; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CTA1-DD; ISCOM; adjuvants; enzyme; vaccine; B cell; Dendritic cell; T cells;

   Sammanfattning : The CTA1-DD/ISCOMs vector is a rationally designed mucosal adjuvant that was developed to host the distinctive properties of either adjuvant alone or in a combination that hosted additive enhancing effects on mucosal immune responses. Here I demonstrate that CTA1-DD can be incorporated into the ISCOM with greatly augmented immunogenicity of both incorporated and admixed antigen. LÄS MER

5. 19. Biosynthetic and synthetic studies of the fungal metabolite galiellalactone

   Författare :Martin H Johansson; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biotechnology; Bioteknik; Organisk kemi; Organic chemistry; enzyme; mycelium; intramolecular Diels-Alder reaction; Diels-Alderase; asymmetric synthesis; biosynthesis; total synthesis; STAT3 inhibition; galiellalactone; fungal metabolite;

   Sammanfattning : Galiellalactone is a fungal metabolite found in the basidiomycetes Galiella rufa and the unidentified strain A111-95. It has been shown to possess promising activities as an inhibitor of the IL-6 mediated STAT3 signaling in HepG2 cells. LÄS MER

7. 20. Physiology of Caldicellulosiruptor saccharolyticus: a hydrogen cell factory

   Författare :Karin Willquist; Teknisk mikrobiologi; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; growth activation; hydrogen tolerance; hydrogen yields CO2 inhibition; physiology; enzyme kinetics; Caldicellulosiruptor saccharolyticus; biohydrogen; energy metabolism;

   Sammanfattning : A high substrate conversion efficiency is a prerequisite for an economically feasible biohydrogen production. Caldicellulosiruptor saccharolyticus is a strictly anaerobic extreme thermophilic bacterium that is able to convert the theoretical maximum of 4 mol/mol glucose to H2. LÄS MER