Sökning: "Biologi med inriktning mot strukturbiologi"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Biologi med inriktning mot strukturbiologi.
1. Of spiders, bugs, and men Structural and functional studies of proteins involved in assembly
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : Protein assembly enables complex machineries while being economical with genetic information. However, protein assembly also constitutes a potential threat to the host, and needs to be carefully regulated.Sulfate is a common source of sulfur for cysteine synthesis in bacteria. LÄS MER
2. Targeting Infectious Disease Structural and functional studies of proteins from two RNA viruses and Mycobacterium tuberculosis
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : The recent emergence of a number of new viral diseases as well as the re-emergence of tuberculosis (TB), indicate an urgent need for new drugs against viral and bacterial infections.Coronavirus nsp1 has been shown to induce suppression of host gene expression and interfere with host immune response. LÄS MER
3. Thiopurine S-methyltransferase - characterization of variants and ligand binding
Detta är en avhandling från Linköping : Linköping University Electronic PressSammanfattning : Thiopurine S-methyltransferase (TPMT) belongs to the Class I S-adenosylmethionine-dependent methyltransferase (SAM-MT) super family of structurally related proteins. Common to the members of this large protein family is the catalysis of methylation reactions using S-adenosylmethionine (SAM) as a methyl group donor, although SAM-MTs act on a wide range of different substrates and carry out numerous biologically important functions. LÄS MER
4. Evolutionary and Pharmacological Studies of NPY and QRFP Receptors
Detta är en avhandling från Uppsala, Sweden : Acta Universitatis UpsaliensisSammanfattning : The neuropeptide Y (NPY) system consists of 3-4 peptides and 4-7 receptors in vertebrates. It has powerful effects on appetite regulation and is involved in many other biological processes including blood pressure regulation, bone formation and anxiety. LÄS MER
5. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). LÄS MER
