Sökning: "Diabetes typ 1"

Visar resultat 6 - 10 av 153 avhandlingar innehållade orden Diabetes typ 1.

  1. 6. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

    Författare :Henrik Borg; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; secreting systems; Endocrinology; seropositive; seronegative; slowly-progressive; Type 2; Type 1; classification; IA-2A; IA-2; GADA; GAD; ICA; islet antibodies; C-peptide; beta cell function; diabetes mellitus; adult-onset; sekretion; diabetologi;

    Sammanfattning : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. LÄS MER

  3. 7. Dissecting the role of micro-RNAs in diabetes

    Författare :Caroline Bolmeson; Create Health; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Type 2 diabetes; micro-RNA; Dicer; beta-cell function; insulin secretion; glucose; NOD mouse; Goto-Kakizaki rat; human islets; thymocytes; apoptosis;

    Sammanfattning : The role of miRNAs in pancreatic islets and β-cell function and in the development of diabetes in human and rodents have been investigated in this thesis. Dicer1 was specifically deleted in vivo in pancreatic β-cells under the RIP-promoter in mice. LÄS MER

  4. 8. Brain function and glucocorticoids in obesity and type 2 diabetes including effects of lifestyle interventions

    Författare :Andreas Stomby; Tommy Olsson; Mats Ryberg; Carl-Johan Boraxbekk; Alasdair MacLullich; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; type 2 diabetes; glucocorticoid; cortisol; 11beta hydroxysteroid dehydrogenase type 1; episodic memory; functional magnetic resonance imaging; paleolithic diet; exercise; Internal Medicine; invärtesmedicin; medicin; Medicine;

    Sammanfattning : Background Obesity and associated metabolic dysregulation are linked to impaired cognitive function and alterations in brain structure, which increases the risk of age-related dementia. Increased glucocorticoid (GC) exposure may be a potential mediator of these negative effects on the brain. LÄS MER

  5. 9. Aspects of gluten in children with type 1 diabetes

    Författare :Hanna Söderström; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Typ 1-diabetes; gluten; celiaki; tillväxt; gluten fri mat; glycol kontroll;

    Sammanfattning : .... LÄS MER

  7. 10. Fibrinolytic factors in relation to anthropometry and incident type 2 diabetes

    Författare :Jenny Hernestål Boman; Lars Johansson; Jan-Håkan Jansson; Tomas Lindahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; folkhälsa; Public health; cardiovascular disease; hjärt- och kärlforskning;

    Sammanfattning : Fibrinolytic imbalance is associated with cardiovascular disease and its risk factors. The longitudinal changes in the fibrinolytic factors tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1) and tPA/PAI-1 complex have been inadequately studied in the general population and in relation to incident type 2 diabetes mellitus (T2DM). LÄS MER