Sökning: "seronegative"

Visar resultat 1 - 5 av 51 avhandlingar innehållade ordet seronegative.

  1. 1. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

    Författare :Henrik Borg; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; secreting systems; Endocrinology; seropositive; seronegative; slowly-progressive; Type 2; Type 1; classification; IA-2A; IA-2; GADA; GAD; ICA; islet antibodies; C-peptide; beta cell function; diabetes mellitus; adult-onset; sekretion; diabetologi;

    Sammanfattning : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. LÄS MER

  3. 2. Human cytomegalovirus (HCMV) : detection and elimination of infected blood cells in vitro, immune reactivity and complications following HCMV infection

    Författare :Susanne Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human cytomegalovirus (HCMV) belongs to the herpes virus family and establishes life-long persistence in a latent state following a primary infection. HCMV disease causes high morbidity in immunosuppressed individuals, such as bone marrow and organ transplant patients. LÄS MER

  4. 3. Vaccine responses after chemotherapy or stem cell transplantation in patients with hematological malignancies

    Författare :Sigrun Einarsdottir; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vaccination; chemotherapy; stem cell transplantation; antibodies; tetanus; diphtheria; polio; Tick-borne encephalitis TBE ; SARS-CoV-2;

    Sammanfattning : The prevention of infections in patients with hematological malignancies is important given the inherent immune deficiency associated with these diseases and the immunosuppressive effects of treatment. This thesis investigated the efficacy of vaccines against various pathogens among patients with hematological disease receiving chemotherapy or stem cell transplantation, including the longevity of vaccine responses. LÄS MER

  5. 4. HIV-1 infection in Tanzania : HIV antibody testing strategies and lymphocyte subset determinations

    Författare :Willy Shileanga Kikoka Urassa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; antibody detection; alternative confirmatory strategy; lymphocyte subsets; Tanzania; Africa.;

    Sammanfattning : The objectives of the studies that are reported in this thesis were to evaluate HIV antibody testing strategies and prognostic markers and to study inummological deterioration of HIV-1 infected individuals. Alternative testing strategies for confirmation of HIV seropositivity were evaluated using combinations of screening assays. LÄS MER

  7. 5. Local and systemic inflammatory mediators and their relation to pressure-pain threshold and pain of the temporomandibular joint

    Författare :Lars Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The first aim of this investigation was to investigate the validity of TMJ pressure-pain threshold for assessment of pain conditions of inflammatory nature in the TMJ. Pressure-pain threshold was recorded from the palpable lateral pole of the TMJ condyle with a hand-held electronic pressure algometer (Somedic Production AB, Sollentuna, Sweden). LÄS MER