Sökning: "GADA"

Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet GADA.

1. 1. Beta cell function in autoimmune diabetes in young adults

   Författare :Carina Törn; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ketoacidosis; insulin treatment; prognostic factors; C-peptide; type 2; type 1; IA-2A; ICA; GADA; IAA; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : This thesis presents the results from a study of the first four years of diabetes in 879 patients aged 15-34 years at diagnosis. The aims of this study were to compare clinical classification with the presence of autoantibodies, to study the natural course of beta cell function during the first years of disease and to define predictive factors for the remaining beta cell function after diagnosis. LÄS MER

3. 2. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

   Författare :Henrik Borg; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; secreting systems; Endocrinology; seropositive; seronegative; slowly-progressive; Type 2; Type 1; classification; IA-2A; IA-2; GADA; GAD; ICA; islet antibodies; C-peptide; beta cell function; diabetes mellitus; adult-onset; sekretion; diabetologi;

   Sammanfattning : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. LÄS MER

4. 3. Gestational Diabetes Mellitus- Future risk for mother and child

   Författare :Charlotta Nilsson; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gestational Diabetes Mellitus; autoantibody; GADA; ZnT8A; C-peptide; overweight; offspring;

   Sammanfattning : Gestational diabetes mellitus (GDM) occurs as a complication in 2% of all pregnancies in Sweden. Women with GDM have a substantial risk of developing type 2 diabetes later in life, but the risk of developing type 1 diabetes is also increased. GDM increases the risk for macrosomia and caesarean delivery. LÄS MER

5. 4. The Diabetes Incidence Study in Sweden (DISS): Ascertainment, risk factors, and problems with classification

   Författare :Bengt Littorin; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1; stress; register; life events; incidence; ICA; family characteristics; GADA; epidemiology; diabetes mellitus; classification; Ascertainment; BMI; type 2; unclassifiable; year of diagnosis.; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : The Diabetes Incidence Study in Sweden (DISS) registers diabetes in young adults aged 15-34 years in Sweden. This thesis aims to validate the ascertainment, methods in the classification of diabetes, and putative etiological factors such as family background, psychological stress, and BMI, that may affect the incidence of diabetes in young adults, in the DISS registry. LÄS MER

7. 5. Epidemiology of diabetes in a well defined population in Sweden: the Skaraborg Diabetes Registry

   Författare :Bo Berger; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; diabetologi; Endokrinologi; diabetology; secreting systems; Endocrinology; Medicin människa och djur ; Medicine human and vertebrates ; IA-2A; GADA; ICA; islet antibodies; C-peptide; mortality; prevalence; serology; transplantation; Immunologi; serologi; Public health; incidence; epidemiology; epidemiologi; sekretion; Folkhälsa;

   Sammanfattning : Time trends in prevalence, incidence and mortality was followed in 15000 diabetic patients in 1991?2005. Clinical findings, C-peptide protocols, and islet antibodies were compared in their ability to distinguish type 1 from type 2 diabetes, and factors associated with the prognosis of diabetes were explored. LÄS MER