Sökning: "DOMAIN PROTEINS"
Visar resultat 1 - 5 av 759 avhandlingar innehållade orden DOMAIN PROTEINS.
1. NA transmembrane domain : Amphiphilic drift to accommodate two functions
Sammanfattning : Neuraminidase (NA) is one of two major antigens on the surface of influenza A viruses. It is comprised of a single N-terminal transmembrane domain (TMD), a stalk domain, and a C-terminal enzymatic head domain that cleaves sialic acid, most notably to release new particles from the host cell surface. LÄS MER
2. Structure-function relationships of hormone-sensitive lipase
Sammanfattning : The primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. LÄS MER
3. Membrane Induced Structure in Transmembrane Signaling Proteins and Peptides : Peptide–Lipid Interactions Studied by Spectroscopic Methods
Sammanfattning : Biological membranes, defining the boundary of cells and eukaryotic organelles, are mainly composed of lipids and membrane proteins. Interactions between these lipids and proteins are needed to preserve the tight seal of the membrane, but also to induce structure for proper function in many membrane proteins. LÄS MER
4. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics
Sammanfattning : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. LÄS MER
5. Characterization of ATP-dependent protein dynamics under native-like conditions
Sammanfattning : Proteins are biological macromolecules capable of accelerating biochemical reactions. To accomplish this, proteins undergo changes in their molecular structure. Advances in structural biology have resulted in ever-increasing numbers of high-resolution protein structures. LÄS MER