Sökning: "chemoselectivity"

Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet chemoselectivity.

  1. 1. Lipase chemoselectivity - kinetics and applications

    Författare :Cecilia Hedfors; Karl Hult; Mats Martinelle; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; Rhizomucor miehei lipase; active site titration; kinetics; chemoselectivity; thiol; alcohol; thiol-functionalized polyesters; Biochemistry; Biokemi;

    Sammanfattning :   A chemoselective catalyst is preferred in a chemical reaction where protecting groups otherwise are needed. The two lipases Candida antarctica lipase B and Rhizomucor miehei lipase showed large chemoselectivity ratios, defined as (kcat/KM)OH / (kcat/KM)SH, in a transacylation reaction with ethyl octanoate as acyl donor and hexanol or hexanethiol as acyl acceptor (paper I). LÄS MER

  3. 2. Iodonium Salts : Preparation, Chemoselectivity and Metal-Catalyzed Applications

    Författare :Joel Malmgren; Berit Olofsson; Jérome Waswer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Diaryliodonium salts; chemoselectivity; heterogeneous catalysis; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis concerns the preparation and use of diaryliodonium salts. In Project I various unsymmetrical diaryliodonium salts were reacted with three different nucleophiles in order to study the chemoselectivity of the reactions of the salts. LÄS MER

  4. 3. Unsymmetrical Diaryliodonium Salts : Development and Chemoselectivity studies

    Författare :Joel Malmgren; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The first part describes a chemoselectivity study on diaryliodonium salts where oxygen, nitrogen and carbon nucleophiles have been arylated. Twelve different unsymmetric phenyl(aryl)iodonium salts were designed with a systematic variation of the steric and electronic properties of the aryl group. LÄS MER

  5. 4. Catalytic Amide Reductions under Hydrosilylation Conditions

    Författare :Alexey Volkov; Hans Adolfsson; Andrei K. Yudin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hydrosilylation; amides; reduction; chemoselectivity; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis covers the development of catalytic methodologies for the mild and chemoselective reductions of amides. The first part of the thesis describes the use of a Fe(II)/NHC catalyst for the deoxygenation of aromatic tertiary amides to corresponding amines. LÄS MER

  7. 5. Development and Applications of Hypervalent Iodine Compounds : Powerful Arylation and Oxidation Reagents

    Författare :Nazli Jalalian; Berit Olofsson; Viktor V. Zhdankin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; hypervalent iodine compounds; diaryliodonium salts; oxidation; Koser s reagent; arylation; phenols; diaryl ethers; chemoselectivity; organisk kemi; Organic Chemistry;

    Sammanfattning : The first part of this thesis describes the efficient synthesis of several hypervalent iodine(III) compounds. Electron-rich diaryliodonium salts have been synthesized in a one-pot procedure, employing mCPBA as the oxidant. Both symmetric and unsymmetric diaryliodonium tosylates can be isolated in high yields. LÄS MER