Sökning: "Amidation"

Visar resultat 6 - 10 av 18 avhandlingar innehållade ordet Amidation.

  1. 6. The Impact of the Neuropeptide Substance P (SP) Fragment SP1-7 on Chronic Neuropathic Pain

    Författare :Anna Jonsson; Fred Nyberg; Mathias Hallberg; James Zadina; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropathic pain; substance P SP ; SP1-7; bioactive fragments; spared nerve injury; spinal cord injury; streptozotocin-induced diabetes; allodynia; hyperalgesia; peptidomimetics; cerebrospinal fluid; spinal cord stimulation; radioimmunoassay; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : There is an unmet medical need for the efficient treatment of neuropathic pain, a condition that affects approximately 10% of the population worldwide. Current therapies need to be improved due to the associated side effects and lack of response in many patients. LÄS MER

  3. 7. Amine Transaminases in Biocatalytic Amine Synthesis

    Författare :Henrik Land; Per Berglund; Helen C. Hailes; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Amine Transaminase; Biocatalysis; Transamination; Reductive Amination; Enzyme; Enzyme Engineering; Equilibrium Displacement; Screening; Enzyme Stability; Bioteknologi; Biotechnology;

    Sammanfattning : The use of enzymes, nature´s own catalysts, both isolated or as whole cells to perform chemical transformations is called biocatalysis. As a complement to classical chemical catalysis, biocatalysis can be an environmentally friendly and more economical option in the production and synthesis of chemicals. LÄS MER

  4. 8. Hyaluronan Derivatives and Injectable Gels for Tissue Engineering

    Författare :Kristoffer Bergman; Tim Bowden; Jöns Hilborn; Jeffrey Hubbell; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hyaluronan; Hydrogel; Tissue Engineering; Scaffold; Minimally invasive strategy; Bone morphogenetic protein; Hydroxyapatite; Bone; Cartilage; Tendon; Polymer chemistry; Polymerkemi;

    Sammanfattning : The present work describes the preparation of hyaluronan derivatives and hydrogels with potential use in tissue engineering applications. A potentially injectable hydrogel consisting of hyaluronan and collagen was successfully used to grow neurons in vitro by encapsulation of neural stem and progenitor cells. LÄS MER

  5. 9. Molecular cloning of genes coding for three inducible antibacterial proteins of Hyalophora cecropia

    Författare :Kleanthis G. Xanthopoulos; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The humoral immune system in the pupa of the giant silk moth Hyalophora cecropia can be induced by an injection of non-pathogenic bacteria. Three families of antibacterial proteins are synthesized, namely lysozyme, the attacins and the cecropins. LÄS MER

  7. 10. Isolation, structure and processing of bioactive peptides

    Författare :Valentina Bonetto; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Amino acid sequences deduced from DNA sequences do not prove in which forms proteins, peptides and their processed products are present in the tissues. The products of a single gene may give rise to variants of peptides because of post-transcriptional or post-translational processing. LÄS MER