Sökning: "Adenine"

Visar resultat 1 - 5 av 68 avhandlingar innehållade ordet Adenine.

  1. 1. Towards novel applications for biomolecular interactions at surfaces

    Författare :Pernilla Söderberg; Karl Hult; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular recognition; interactions; phage display; biomolecular interactions; phage; adenine; influenza virus replication; oseltamivir; imprinted polymers.;

    Sammanfattning : The focus of this thesis has been to examine two new concepts involving the interaction of biological agents with synthetic material surfaces.The feasibility of deploying phage display techniques for the screening of materials in non-biological media was examined in two studies. LÄS MER

  3. 2. Quantum Chemical Studies of Chemotherapeutic Drug Cisplatin : Activation and Binding to DNA

    Författare :Johan Raber; David van der Spoel; Paolo Carloni; Uppsala universitet; []
    Nyckelord :Quantum chemistry; cisplatin; quantum chemistry; DNA; density functional theory; activation; JM118; substitution reaction; Platinum; guanine; adenine; cytostatic drug; aquation; anation; activation; Kvantkemi;

    Sammanfattning : The serendipitous discovery of the potent cytotoxic properties of cisplatin brought about a revolution in the treatment of certain types of cancer, but almost fifty years later, there still remain unknown areas in the chemistry of cisplatin. There are questions regarding which form of the drug reaches its DNA target, or why certain DNA sequences are more preferred than others for reaction with cisplatin. LÄS MER

  4. 3. Towards First-Principles Understanding of Biomolecular Adsorption

    Författare :Svetla Chakarova Käck; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DFT; phenol; adenine; graphite; biomolecules; van der Waals interactions; denaturation; protein; lattice models; PAH dimers; adsorption;

    Sammanfattning : A fundamental understanding of the interactions of biomolecules, such as proteins and DNA, with surfaces is of immense importance in numerous applications and poses a true challenge for theory. Density functional theory (DFT) is a quantum-mechanical tool well established for its ability to balance large system size with good accuracy in first-principles studies. LÄS MER

  5. 4. Collision- and photon-induced dynamics of complex molecular ions in the gas phase

    Författare :Linda Giacomozzi; Henning Zettergren; Jason Greenwood; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAHs; Porphyrins; Adenine; Flavins; Biomolecules; Collisions; Experiments; Reactions; Non-Statistical Fragmentation; Molecular Dynamics; Photon-Induced Fragmentation; Luminescence; Photoisomerization; Proton Transfer; fysik; Physics;

    Sammanfattning : In this thesis, I report experiments probing collision- and photon-induced molecular dynamics in the gas phase. Excited molecules formed in such interactions may relax by emitting electrons or photons, isomerization or fragmentation. LÄS MER

  7. 5. Intramolecular processes in the excited state of biologically important systems : a spectroscopic study

    Författare :Joakim Andreasson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; adenine; porphyrins; photophysics; spectroscopy; DNA-nases;

    Sammanfattning : .... LÄS MER