Sökning: "5 -Guanylic Acid"

Visar resultat 1 - 5 av 1703 avhandlingar innehållade orden 5 -Guanylic Acid.

  1. 1. A theoretical study of 5-Aminolevulinic acid and its esters : properties and lipid permeability

    Författare :Edvin Erdtman; Leif Eriksson; Fahmi Himo; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysical chemistry; Biofysikalisk kemi; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : 5-aminolevulinic acid (5ALA) is a widely used prodrug in Photodynamic therapy (PDT). The target molecule in 5ALA-PDT is Protoporphyrin IX (PpIX), which is synthesized endogenously via the heme pathway in the cell. LÄS MER

  2. 2. Levulinic Acid : Versatile Building Block for Plasticizer Design

    Författare :Wenxiang Xuan; Minna Hakkarainen; Karin Odelius; Rafael Auras; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; levulinic acid; plasticizer; polylactide; migration; degradation; antibacterial;

    Sammanfattning : The utilization of renewable resources is a challenging and an importantaspect towards development of sustainable plastic products. Therefore,commercial biomass conversion to produce biobased chemicals isnecessary to replace current fossil-based chemicals. LÄS MER

  3. 3. 5-HT2A : a serotonin receptor with a possible role in joint diseases

    Författare :Anders Kling; Solbritt Rantapää-Dahlqvist; Carl-Olav Stiller; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 5-HT2A serotonin receptor; serotonin; rheumatoid arthritis; adverse drug reaction; HTR2A; glucocorticoids; klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : BackgroundSerotonin (5-HT), an amino acid derivative and neurotransmitter, has for long been studied in relation to inflammation. It is an endogenous ligand for several different types of serotonin receptors. The serotonin receptor 5-HT2A has been reported to have a role in the pathophysiology of arthritis in animal experiment models. LÄS MER

  4. 4. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions

    Författare :Edvin Erdtman; Leif Eriksson; Tore Brinck; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-Aminolevulinic acid; tautomerization; PDT; DFT; MM; QM MM; Porphobilinogen synthase; Uroporphyrinogen III decarboxylase; membrane penetration; enzyme mechanism; Biophysical chemistry; Biofysikalisk kemi; Quantum chemistry; Kvantkemi; Theoretical chemistry; Teoretisk kemi; Fysikalisk kemi; Physical Chemistry; Biochemistry; Biokemi;

    Sammanfattning : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. LÄS MER

  5. 5. Exploring eicosanoids as biomarkers in severe chronic rhinosinusitis with nasal polyps

    Författare :Axel Nordström; Maria Kumlin; Marie Svedberg; Mattias Jangard; Michael Ryott; Gunnar Nilsson; Sophiahemmet Högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Chronic rhinosinusitis (CRS) is one of the most common inflammatory chronic conditions, leading to a persistent nasal congestion, nasal discharge, and a loss of smell. Despite sinus surgery and frequent use of oral corticosteroids, a large proportion of individuals with CRS are difficult to treat and have recurrent inflammation. LÄS MER