Sökning: "PDT"
Visar resultat 1 - 5 av 35 avhandlingar innehållade ordet PDT.
1. Methods, Instrumentation and Mechanisms for Optical Characterization of Tissue and Treatment of Malignant Tumours
Sammanfattning : In this thesis, different optical methods utilising visible light for characterization of tissue have been developed and evaluated. The feasibility of many of these methods has been demonstrated in the laboratory or in animal experiments. LÄS MER
2. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions
Sammanfattning : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. LÄS MER
3. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery
Sammanfattning : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. LÄS MER
4. Primary and Secondary Outcomes from a Double Randomized Clinical Preference Trial of two Panic-Focused Psychotherapies
Sammanfattning : Approximately 2-3% of adults in Sweden will experience unexpected panic attacks that cause them to develop fears of future attacks and to alter their lives, defined as Panic Disorder with or without Agoraphobia (PD/A). The condition often onsets in late adolescence or early adulthood, with high levels of psychiatric comorbidity, social difficulties, diminished study and work ability, an elevated risk for substance use, health problems, and mortality. LÄS MER
5. Photodynamic therapy and laser-based diagnostic studies of malignant tumours
Sammanfattning : Two non-thermal regimens of light interaction with biological tissue, that are in a natural way connected, are discussed in the present thesis. These are photodynamic therapy (PDT) for the treatment of malignant tumours and laser-induced fluorescence (LIF) for tissue characterization. LÄS MER