Sökning: "Solbritt Rantapää-Dahlqvist"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Solbritt Rantapää-Dahlqvist.

  1. 1. Genetic markers in rheumatoid arthritis

    Författare :Solbritt Rantapää Dahlqvist; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; family history; genetic marker; HLA B27; HLA DR4; properdin factor B; C3 complement; -antitrypsin; haptoglobin; transferrin;

    Sammanfattning : Genetic as well as environmental factors are believed to be of importance in the etiology of rheumatoid arthritis (RA). There are a number of previous studies of genetic markers in RA, but so far no genetic linkage and only a few associations have been found. Of the associations only one (with the HLA antigen DR4) appears to be well documented. LÄS MER

  2. 2. Predictors of disease onset and progression in early rheumatoid arthritis : A clinical, laboratory and radiological study

    Författare :Ewa Berglin; Solbritt Rantapää-Dahlqvist; Thomas Skogh; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; early; rheumatoid; arthritis; anti-CCP; antibodies; factors; radiological; outcome; disease; onset; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. LÄS MER

  3. 3. Early rheumatoid arthritis : biomarkers and hormonal factors in relation to disease progression

    Författare :Antonia Boman; Solbritt Rantapää-Dahlqvist; Ewa Berglin; Gerd-Marie Alenius; Mikael Brink; Heidi Kokkonen; Inger Gjertsson; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Early rheumatoid arthritis; biomarker; ACPA; RANKL; disease activity; radiological destruction; cardiovascular events; hormonal factors; reumatologi; rheumatology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, affecting approximately 0.5 to 1% of the adult population. Although the aetiology is not fully known, a complex interaction between genetic, environmental and stochastic factors is thought to trigger the pathogenic mechanisms. LÄS MER

  4. 4. Presence of immunological markers preceding the onset of rheumatoid arthritis

    Författare :Mikael Brink; Solbritt Rantapää Dahlqvist; Anca Irinel Catrina; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; rheumatoid arthritis; anti citrullinated protein antibodies; pre-symptomatic individual; immunologi; Immunology; reumatologi; rheumatology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease with an unknown aetiology characterized by joint destruction. Both genetic and environmental factors contribute to the disease development with HLA-DRB1* alleles and smoking identified as most important. LÄS MER

  5. 5. Immunological mechanisms in systemic autoimmunity : autoantibodies and chemokines in systemic lupus erythematosus and during treatment with TNF inhibitors in rheumatoid arthritis

    Författare :Catharina Eriksson; Karl-Gösta Sundqvist; Solbritt Rantapää-Dahlqvist; Mari Norgren; Thomas Skogh; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; autoimmunity; chemokines; T-cells; autoantibodies; CD91; Clinical immunology; Klinisk immunologi; Rheumatology; Reumatologi; Clinical Immunology; klinisk immunologi; reumatologi; rheumatology;

    Sammanfattning : Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without powerful treatment, may lead to irreversible joint damage. During the past decade, anti-cytokine therapy has become available, e.g. LÄS MER