Sökning: "warfarin"

Visar resultat 6 - 10 av 64 avhandlingar innehållade ordet warfarin.

  1. 6. Two worlds, one goal : A Clinician’s Perspective on Laboratory Analyses in Anticoagulant Treatment

    Författare :Kerstin Arbring; Tomas Lindahl; Srinivas Uppugunduri; Margareta Holmström; Gerd Lärfars; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; Warfarin; DOAC; PT-INR; VKORC1;

    Sammanfattning : Almost precisely a century ago, in the 1920s and 1930s, cattle bled to death in North America after being fed moldy hay containing sweet clover, the yellow Melilotus officinalis, and the white Melilotus albus. The toxic substance in the hay inhibiting blood coagulation was identified and named dicumarol. LÄS MER

  3. 7. Anticoagulants in kidney disease

    Författare :Frida Welander; Anders Själander; Henrik Holmberg; Emöke Dimény; Marie Evans; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; atrial fibrillation; chronic kidney disease; dialysis; DOAC; ischemic stroke; major bleeding; nephrotic syndrome; venous thromboembolism; warfarin.; Medicine; medicin;

    Sammanfattning : Background: Patients with chronic kidney disease (CKD) and atrial fibrillation (AF) are at high risk of ischemic stroke. Evidence is lacking if patients with advanced CKD or on dialysis benefit from oral anticoagulants (OAC) as stroke prophylaxis. LÄS MER

  4. 8. Oral anticoagulation and stroke risk

    Författare :Vilhelm Sjögren; Anders Själander; Per Wester; Peter J Svensson; Mia von Euler; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; warfarin; atrial fibrillation; dabigatran; rivaroxaban; apixaban; low-molecular-weight heparin; bridging;

    Sammanfattning : Background: The risk of ischaemic stroke in patients with atrial fibrillation (AF) and mechanical heart valve (MHV) prostheses can be reduced by oral anticoagulation (OAC), which increases the risk of serious bleeding. The aims of this thesis were [1] to find out how effective and safe warfarin is where treatment quality is high, i.e. LÄS MER

  5. 9. Oral anticoagulation treatment in atrial fibrillation - To bleed or not to bleed, that is the question

    Författare :Mattias Wieloch; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anticoagulation; atrial fibrillation; hemorrhage; kidney; warfarin; epidemiology; stroke;

    Sammanfattning : Background: Oral antigoagulation treatment (OAT) with warfarin have a narrow therapeutic window and patients exhibit a highly variable doseresponse that is attributable to genetic, disease-related,and environmental factors as well as prescription and nonprescription drugs, dietary vitamin K and alcohol. The effect of warfarin treatement on blood coagulation is measured using international normalized ratio (INR). LÄS MER

  7. 10. Pro- and anticoagulant mechanisms in coronary artery disease. Clinical studies on factor VII and resistance to activated protein C

    Författare :Johan Holm; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein C; Factor VII; blood coagulation; myocardial infarction; APC resistance; Cardiovascular system; Kardiovaskulära systemet; warfarin;

    Sammanfattning : The triggering mechanism in myocardial infarction (MI) and unstable angina involves coronary thrombus formation following plaque rupture. Coagulation is initiated by tissue factor that activates factor VII (FVII), and is inhibited by protein C and its co-factor protein S. LÄS MER