Sökning: "low-molecular-weight heparin"

Visar resultat 1 - 5 av 28 avhandlingar innehållade orden low-molecular-weight heparin.

  1. 1. Clinical aspects on treatment of deep venous thrombosis with a low molecular weight heparin

    Författare :Margareta Holmström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Dalteparin is a low molecular weight heparin (LMWH) with a mean mw of 4-6000 D. Compared to unfractionated heparin (UFH), a higher bioavailability, a longer half-life and a more predictable dose-response is achieved after subcutaneous injections. LÄS MER

  2. 2. Endothelial and cardiac effects of 5-fluorouracil. An experimental and clinical study

    Författare :Sara Kinhult; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; endothelin; onkologi; Cytologi; cancer; von Willebrand factor; thrombomodulin; lipoperoxidation; probucol; low-molecular weight heparin; scanning electron microscopy; 5-fluorouracil; endothelium;

    Sammanfattning : The cytostatic drug 5-fluorouracil (5-FU) has been shown to affect both morphology and function of vascular endothelium. These effects could be part of the pathophysiology for 5-FU induced cardiotoxicity. The present thesis explores the mechanisms of this endothelial toxicity. LÄS MER

  3. 3. Multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease

    Författare :Tomas Jernberg; Uppsala universitet; []
    Nyckelord :Medical sciences; ST-monitoring; electrocardiography; vectorcardiography; myocardial infarction; unstable angina; prognosis; low-molecular-weight heparin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : This study evaluated the use of multi-lead ST-monitoring in the early assessment of patients with suspected or confirmed unstable coronary artery disease (UCAD).At continuous 12-lead ECG (c12ECG), the definition of an ischemic episode as a transient ST-deviation ¡Ý0 for at least 1 minute resulted in a good observer agreement (kappa=0. LÄS MER

  4. 4. Oral anticoagulation and stroke risk

    Författare :Vilhelm Sjögren; Anders Själander; Per Wester; Peter J Svensson; Mia von Euler; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; warfarin; atrial fibrillation; dabigatran; rivaroxaban; apixaban; low-molecular-weight heparin; bridging;

    Sammanfattning : Background: The risk of ischaemic stroke in patients with atrial fibrillation (AF) and mechanical heart valve (MHV) prostheses can be reduced by oral anticoagulation (OAC), which increases the risk of serious bleeding. The aims of this thesis were [1] to find out how effective and safe warfarin is where treatment quality is high, i.e. LÄS MER

  5. 5. Studies of ankle fractures : classification, epidemiology, complications and results

    Författare :Hans Juto; Per Morberg; Magnus Hultin; Michael Möller; Sari Ponzer; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ankle fracture; Swedish Fracture Register; AO OTA-classification; epidemiology; venous thromboembolic event; low-molecular-weight heparin; sick leave; outcome; Orthopaedics; ortopedi;

    Sammanfattning : The ankle fracture is one of the most common fractures in adult patients and is a heterogeneous group of fractures. From the fully stable fracture on the most distal part of thefibula to severely unstable and even dislocated ankles. Patients with ankle fractures often report a good result after treatment, but a small group have persistent problems. LÄS MER