Sökning: "apixaban"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet apixaban.
1. Venous thromboembolism: Risk factors, comorbidities, and treatment-associated risk of bleedings
Sammanfattning : Background: Venous thromboembolism (VTE) is the third most common cardiovascular disease, consisting mainly of deep vein thrombosis (DVT) and pulmonary embolism (PE). Since VTE often is a preventable disease, knowledge of risk factors is critical. Following a VTE, many patients are subjected to extended anticoagulant treatment. LÄS MER
2. Oral anticoagulation and stroke risk
Sammanfattning : Background: The risk of ischaemic stroke in patients with atrial fibrillation (AF) and mechanical heart valve (MHV) prostheses can be reduced by oral anticoagulation (OAC), which increases the risk of serious bleeding. The aims of this thesis were [1] to find out how effective and safe warfarin is where treatment quality is high, i.e. LÄS MER
3. Monitoring of the oral anticoagulants apixaban and rivaroxaban to optimize individual safety and efficacy
Sammanfattning : The oral anticoagulants apixaban and rivaroxaban are administered at fixed doses without requiring routine monitoring. However, there is a dose and exposure dependency in efficacy and safety, and monitoring the anticoagulants may improve treatment outcomes. LÄS MER
4. Effects of direct oral anticoagulant treatment on hemostasis in patients with atrial fibrillation
Sammanfattning : The direct oral anticoagulants (DOAC) – dabigatran, rivaroxaban, apixaban and edoxaban – were approved without the need for routine monitoring. However, in parallel with clinical implementation, studies on how to measure the effect of DOACs have become a research area of increasing interest during the last decade. LÄS MER
5. Adherence to drug treatment and interpretation of treatment effects
Sammanfattning : Suboptimal adherence to medical treatments is prevalent across several clinical conditions and can lead to treatment failure. Adherence is a far from fully explored phenomenon and there is little knowledge about how patients interpret treatment effects. LÄS MER