Sökning: "DOAC"

Hittade 4 avhandlingar innehållade ordet DOAC.

  1. 1. Two worlds, one goal : A Clinician’s Perspective on Laboratory Analyses in Anticoagulant Treatment

    Författare :Kerstin Arbring; Tomas Lindahl; Srinivas Uppugunduri; Margareta Holmström; Gerd Lärfars; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; Warfarin; DOAC; PT-INR; VKORC1;

    Sammanfattning : Almost precisely a century ago, in the 1920s and 1930s, cattle bled to death in North America after being fed moldy hay containing sweet clover, the yellow Melilotus officinalis, and the white Melilotus albus. The toxic substance in the hay inhibiting blood coagulation was identified and named dicumarol. LÄS MER

  3. 2. Anticoagulants in kidney disease

    Författare :Frida Welander; Anders Själander; Henrik Holmberg; Emöke Dimény; Marie Evans; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; atrial fibrillation; chronic kidney disease; dialysis; DOAC; ischemic stroke; major bleeding; nephrotic syndrome; venous thromboembolism; warfarin.; Medicine; medicin;

    Sammanfattning : Background: Patients with chronic kidney disease (CKD) and atrial fibrillation (AF) are at high risk of ischemic stroke. Evidence is lacking if patients with advanced CKD or on dialysis benefit from oral anticoagulants (OAC) as stroke prophylaxis. LÄS MER

  4. 3. Effects of direct oral anticoagulant treatment on hemostasis in patients with atrial fibrillation

    Författare :Viktor Schutz Taune; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The direct oral anticoagulants (DOAC) – dabigatran, rivaroxaban, apixaban and edoxaban – were approved without the need for routine monitoring. However, in parallel with clinical implementation, studies on how to measure the effect of DOACs have become a research area of increasing interest during the last decade. LÄS MER

  5. 4. Drug safety and effectiveness in relation to kidney function : a pharmacoepidemiological approach

    Författare :Marco Trevisan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kidney function plays an important role in drug safety and effectiveness. As many medications are excreted by the kidneys, patients with reduced kidney function are at a higher risk of supra-therapeutic or toxic drug levels. LÄS MER