Sökning: "warfarin"

Visar resultat 21 - 25 av 64 avhandlingar innehållade ordet warfarin.

  1. 21. The in-vitro and in-vivo metabolism of the oral anticoagulant phenprocoumon as influenced by genetic polymorphisms of cytochrome P4502C9

    Författare :Mike Ufer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Drug metabolism; cytochrome P450; genetic polymorphism; genotyping; CYP2C9; phenprocoumon; warfarin; acenocoumarol; oral anticoagulants;

    Sammanfattning : Oral anticoagulants are widely used for the prevention of thromboembolic disorders. Warfarin (WA) is most commonly used world-wide, while phenprocoumon (PPC) is the first-line anticoagulant in some European countries including Germany. Each anticoagulant exists in two different enantiomeric forms and is administered orally as a racemate. LÄS MER

  3. 22. Antithrombotic treatment of atrial fibrillation before and after the introduction of non-vitamin K antagonist oral anticoagulants (NOAC) in the Stockholm health care region

    Författare :Tomas Forslund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atrial fibrillation (AF) is the most common cardiac arrhythmia and the major risk factor for thromboembolic stroke. Effective treatment with the oral anticoagulant (OAC) warfarin has been available for decades. However warfarin treatment is complicated, and demands dose adjustments and regular monitoring. LÄS MER

  4. 23. Outcome of Stroke Prevention : Analyses Based on Data from Riks-Stroke and Other Swedish National Registers

    Författare :Signild Åsberg; Andreas Terént; Hélène Pessah; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Epidemiology; Age groups; Risk factors; Atrial fibrillation; Secondary prevention; Anticoagulants; Antiplatelets; Hemorrhage; Mortality.; Medicinsk vetenskap; Medical Science;

    Sammanfattning : The aim of this thesis was to explore variations in stroke prevention and the effect of prevention on outcome. The studies were based on patients registered in the Swedish Stroke Register between 2001 and 2009 and although used to different extents in each paper, additional information was retrieved through linkage to The National Patient Register, the Cause of Death Register, the Prescribed Drug Register and the Total Population Register. LÄS MER

  5. 24. Paroxysmal atrial fibrillation : prognostic implications

    Författare :Leif Friberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is based on data from the Stockholm Cohort on Atrial Fibrillation (SCAF). This cohort consists of all 2912 patients with atrial fibrillation or flutter who were treated as in or outpatients at South Hospital in Stockholm or at Gustavsberg Primary Care Centre during 2002. LÄS MER

  7. 25. Thrombotic and cardiac disease in the antiphospholipid syndrome

    Författare :Giorgia Grosso; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The antiphospholipid syndrome (APS) is a highly heterogeneous disease that presents with obstetric complications and/or thromboembolic events that can hit any side of the vascular tree in an unpredictable way. The common trait among all patients affected by the syndrome is the persistent presence of the antiphospholipid antibodies (aPL) and/or a prolonged coagulation time in vitro, the lupus anticoagulant (LA) test. LÄS MER