Sökning: "voltage clamp"

Visar resultat 6 - 10 av 40 avhandlingar innehållade orden voltage clamp.

  1. 6. Voltage-dependent anion channels (VDAC) in the plasma membrane induce apoptosis

    Författare :Nesar Akanda; Fredrik Elinder; Tuula Jalonen; Linköpings universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Physiology; Apoptosis; Cell membrane; Hippocampus; Membrane potentials; Neurons; Voltage-dependent anion channels; Medicine; Medicin;

    Sammanfattning : Apoptosis, or programmed cell death, is essential for proper development and functioning of the body systems. During development, apoptosis plays a central role to sculpt the embryo, and in adults, to maintain tissue homeostasis by eliminating redundant, damaged or effete cells. Therefore, a tight regulation of this process is essential. LÄS MER

  3. 7. Polyunsaturated Fatty Acids Modifying Ion Channel Voltage Gating

    Författare :Sara Börjesson; Fredrik Elinder; Klaus Benndorf; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Voltage-gated ion channels play fundamental roles in neuronal excitability and therefore dysfunctional channels can cause disease. Epilepsy is such a disease, affecting about 1% of the population and being characterized by synchronous electric activity of large groups of neurons leading to various types of seizures. LÄS MER

  4. 8. Calcium channel activity and force regulation in smooth muscle: Effects of polyamines and growth stimulation

    Författare :Maria Gomez; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; verapamil; tissue culture; portal vein; patch-clamp; calcium; spermidine; spermine; polyamines; excitation-contraction; smooth muscle; calcium channel; ionomycin.; Physiology; Fysiologi;

    Sammanfattning : The initial signal for contraction in smooth muscle is an increase in [Ca2+]i. Ca2+ ions can either enter the cytosol from the extracellular medium or be released from intracellular stores. Voltage-operated Ca2+ channels (VOC) play a dominant role in the activation of smooth muscle contraction. LÄS MER

  5. 9. The electrophysiological response of medial preoptic neurons to hypoxia and development of a system for patch-clamp measurement with full oxygen control

    Författare :Nazanin Bitaraf; Ronnie Lundström; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medical Engineering for Healthcare; Medicinsk teknik för hälsovård;

    Sammanfattning : A stroke is caused by interruption of the blood supply to the brain. Yearly 15 million people around the globe endure a stroke and the costs and suffering for the people involved and the society are immense. LÄS MER

  7. 10. Roles of voltage-gated Ca2+ channel subunits in pancreatic β cells

    Författare :Abdulla S. Kazim; Diabetes - öpatofysiologi; []
    Nyckelord :diabetes; Type 2 diabetes T2D ; Ca2 ; Ca2 channels; subunits;

    Sammanfattning : Hallmarks of type 2 diabetes (T2D) include elevated blood glucose and free fatty acids (FFAs) as a result of impaired β cell insulin secretion and decreased β cell mass. The glucose-stimulated insulin secretion (GSIS) in β cells is triggered by depolarization-evoked Ca2+ entry through voltage-gated Ca2+ (CaV) channels. LÄS MER