Sökning: "Abdulla S. Kazim"

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1. 1. Roles of voltage-gated Ca2+ channel subunits in pancreatic β cells

   Författare :Abdulla S. Kazim; Diabetes - öpatofysiologi; []
   Nyckelord :diabetes; Type 2 diabetes T2D ; Ca2 ; Ca2 channels; subunits;

   Sammanfattning : Hallmarks of type 2 diabetes (T2D) include elevated blood glucose and free fatty acids (FFAs) as a result of impaired β cell insulin secretion and decreased β cell mass. The glucose-stimulated insulin secretion (GSIS) in β cells is triggered by depolarization-evoked Ca2+ entry through voltage-gated Ca2+ (CaV) channels. LÄS MER