Sökning: "vital microscopy"

Visar resultat 16 - 20 av 68 avhandlingar innehållade orden vital microscopy.

1. 16. Digital holography and image processing methods for applications in biophysics

   Författare :Hanqing Zhang; Magnus Andersson; Krister Wiklund; Wählby Carolina; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Digital holographic microscopy; image processing; image reconstruction; bacterial adhesion; cell morphology; algorithm development; software design; quantitative measurement; microfluidics; multidisciplinary research; signalbehandling; Signal Processing; teknisk fysik med inriktningen mikrosystemteknik; engineering science with specialization in microsystems technology;

   Sammanfattning : Understanding dynamic mechanisms, morphology and behavior of bacteria are important to develop new therapeutics to cure diseases. For example, bacterial adhesion mechanisms are prerequisites for initiation of infections and for several bacterial strains this adhesion process is mediated by adhesive surface organelles, also known as fimbriae. LÄS MER

3. 17. Thermally Induced Fracture Performance of Asphalt Mixtures

   Författare :Prabir Kumar Das; Björn Birgisson; Dallas Little; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Low temperature cracking; asphalt concrete fracture mechanics; viscoelasticity; non-linear thermal contraction coefficient; atomic force microscopy; wax; wax crystallization; SRA - Transport; SRA - Transport;

   Sammanfattning : A major distress mode in asphalt pavements is low temperature cracking, which results from the contraction and expansion of the asphalt pavement under extreme temperature changes. The potential for low temperature cracking is an interplay between the environment, the road structure and importantly the properties of the asphalt mixture. LÄS MER

4. 18. Structural Insights into the Acquisition and Storage of Iron

   Författare :Ulrika Schagerlöf; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Strukturkemi; Molecular biophysics; Molekylär biofysik; Structure chemistry; single particle; ferric reductase; human phagocyte superoxide-generating NADPH oxidase; frataxin; cryo electron microscopy; FRO2; iron homeostasis; iron acquisition;

   Sammanfattning : It is of vital importance to understand the systems for iron metabolism and this thesis contributes to this by providing insights into the structure and function of the acquisition and homeostasis of iron. The two proteins that have been primarily investigated are a ferric reductase from Arabidopsis thaliana called FRO2 and a mitochondrial iron chaperone from Saccharomyces cerevisiae called frataxin. LÄS MER

5. 19. Insights into structure and dynamics of the AAA+ motor of magnesium chelatase

   Författare :Joakim Lundqvist; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatik; biomathematics biometrics; Bioinformatics; medical informatics; Rhodobacter capsulatus; Tetrapyrrole; Mutants; Magnesium chelatase; Cryo-Electron microscopy single-particle 3D reconstruction; Chlorophyll biosynthesis; AAA proteins; ATPase; medicinsk informatik; biomatematik; Molecular biophysics; Molekylär biofysik; Natural science; Naturvetenskap;

   Sammanfattning : The insertion of Mg2+ into protoporphyrin IX represents the first committed step in the chlorophyll and bacteriochlorophyll biosynthetic pathways. The reaction is catalyzed by the multisubunit enzyme Mg-chelatase, which consists of three subunits, known as I (molecular weight ~40 kDa), D (~70 kDa), and H (~140 kDa). LÄS MER

7. 20. Bacterial virulence and adaptation mediated by two-component system signalling

   Författare :Henrik Tomenius; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Virulence; atomic force microscopy; biofilm; adaptation; two-component system; signal transduction; gene regulation; phosphorylation; BarA; UvrY;

   Sammanfattning : One of the most fundamental ways of signal perception and propagation is mediated by the bacterial two-component system (TCS). These types of systems mediate bacterial adaptation that may cause disease in a host due to expression of virulence factors. LÄS MER