Sökning: "tyrosine"

Visar resultat 1 - 5 av 617 avhandlingar innehållade ordet tyrosine.

  1. 1. Trapping Tyrosine Z : Exploring the Relay between Photochemistry and Water Oxidation in Photosystem II

    Författare :Johannes Sjöholm; Stenbjörn Styring; Fikret Mamedov; A. William Rutherford; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Photosystem II; Tyrosine Z; EPR; proton-coupled electron transfer; hydrogen bond; pH;

    Sammanfattning : Photosystem II is unique! It remains the only enzyme that can oxidize water using light as energy input. Water oxidation in photosystem II is catalyzed by the CaMn4 cluster. The electrons extracted from the CaMn4 cluster are transferred to P680+ via the tyrosine residue D1-Tyr161 (YZ). LÄS MER

  2. 2. The Tyrosine Kinase GTK : Signal Transduction and Biological Function

    Författare :Cecilia Annerén; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinases; GTK; SHB; proliferation; survival; differentiation; β cells; pancreatectomy; cytokines; diabetes; PC12 cells; NGF; streptozotocin; focal adhesion kinase; RAP1; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. LÄS MER

  3. 3. Using de novo design proteins to explore tyrosine radicals and cation-π interactions

    Författare :Bruce W. Berry; Cecilia Tommos; Anders Hofer; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; tyrosine; radicals; cation-pi interactions; de novo designed proteins; biochemistry; biophysics; biokemi; Biochemistry;

    Sammanfattning : Redox cofactors and amino-acid free radicals play important roles in biology. Although many of the same cofactors and amino acids that form these radicals are found across a broad range of biological systems, identical cofactors can have different reduction potentials. The local environment plays a role in defining these redox potentials. LÄS MER

  4. 4. Functional characterization of tyrosine and tryptophan transport in fibroblasts from healthy controls, patients with schizophrenia and bipolar disorder

    Författare :Ravi Vumma; Nikolaos Venizelos; Tommy Lewander; Dimitrios Kyriakidis; Örebro universitet; []
    Nyckelord :Fibroblasts; Tyrosine; Tryptophan; LAT1; Schizophrenia; Bipolar disorder; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

    Sammanfattning : .... LÄS MER

  5. 5. Signal Transduction by Proline-Rich Tyrosine Kinase Pyk2

    Författare :Inga Dikic; Olli Silvennoinen; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; Protein phosphorylation; tyrosine kinase; Pyk2 FAK; neuronal differentiation; Ras MAP kinase pathway; Oncology; Onkologi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : The proline-rich tyrosine kinase (Pyk2) together with focal adhesion kinase (FAK) define a family of non-receptor protein tyrosine kinases that are regulated by diverse stimuli. Activation of Pyk2 has been implicated in multiple signaling events, including modulation of ion channels, activation of MAP kinase cascades and apoptotic cell death. LÄS MER