Sökning: "tympanic membrane perforations"

Hittade 5 avhandlingar innehållade orden tympanic membrane perforations.

1. 1. The effects of plasminogen deficiency on the healing of tympanic membrane perforations

   Författare :Annika Hansson; Sten Hellström; Diana Berggren; Tor Ny; Magnus von Unge; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tympanic membrane; macrophages; neutrophils; fibrin ogen ; inflammation; keratinocyte migration; wound healing; uPA; tPA; in vitro; Otorhinolaryngology; Otorhinolaryngologi;

   Sammanfattning : The healing of tympanic membrane (TM) perforations is a complex wound healing process including inflammation, migration of keratinocytes and tissue remodelling. Most TM perforations in human heal spontaneously, however some perforations become chronic, and the reason to why is still largely unknown. LÄS MER

3. 2. Healing of tympanic membrane perforations : an experimental study

   Författare :Anisur Rahman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Embryonic stem cells; Healing; Immunosuppressive; Laser; Mesenchymal stem cells; Moiré interferometry; Myringotomy; Perforation; Tympanic membrane;

   Sammanfattning : Most acute tympanic membrane perforations heal spontaneously without any residual complication, whereas a fraction transforms into a chronic perforation. The current treatment of a chronic perforation is surgical repair, which is a costly, time consuming and uncomfortable procedure particularly for the pediatric patients. LÄS MER

4. 3. Transmyringeal middle ear ventilation : an experimental approach to evaluation of its benefits and consequences

   Författare :Ove Söderberg; Sten Hellström; Lars-Eric Stenfors; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Middle ear; tympanic membrane; otitis media; heat myringotomy; laser myringotomy; tympanostomy tube; transmyringeal ventilation;

   Sammanfattning : A prerequisite for a functioning middle ear is an air-filled middle ear cavity. Aeration of the middle ear cavity is controlled by the Eustachian tube. Dysfunction of the Eustachian tube has long been acknowledged as a significant etiological factor in disorders of the middle ear, especially middle ear effusions. LÄS MER

5. 4. Plasminogen : a novel inflammatory regulator that promotes wound healing

   Författare :Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. LÄS MER

7. 5. Multifunctional roles of plasmin in inflammation : Studies of animal models on rheumatoid arthritis, multiple sclerosis, wound healing and infection

   Författare :Jinan Li; Peter Carmeliet; Umeå universitet; []
   Nyckelord :Plasmin; complement; inflammation; wound healing; infection; autoimmune disease; non-autoimmune disease; rheumatoid arthritis; multiple sclerosis; tympanic membrane; otitis media; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : Plasmin has been suggested to be involved in degradation of extracellular matrix (ECM) and tissue remodeling during a number of physiological and pathological processes. The aims of this thesis were to study the functional roles of plasmin during pathological inflammation in autoimmune and nonautoimmune disease models of rheumatoid arthritis (RA), multiple sclerosis (MS), wound healing and infection. LÄS MER