Sökning: "diabetic wounds"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden diabetic wounds.

  1. 1. Plasminogen : a novel inflammatory regulator that promotes wound healing

    Författare :Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. LÄS MER

  3. 2. Studies of chronic ulcers and larval therapy

    Författare :Helene Wolff; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic ulcers; wounds; larval therapy maggot; MRSA; debriding; proteases; larval therapy; maggot; debriding. proteases;

    Sammanfattning : Our aims in this study were to learn more about chronic ulcer pathogenesis (Paper I) and larval therapy (Paper II-V).Materials and methods: Paper I: 26 bacterial isolates of P. aeruginosa from chronic ulcers were examined by PCR technique for detection of the genes of two virulence factors (elastase and alkaline proteinase). LÄS MER

  4. 3. New pathogenic mechanisms in diabetic wound healing

    Författare :Vivekananda Sunkari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetic foot ulcers (DFU) represent one of the most feared and invalidating complication of diabetes with high financial pressure for the healthcare system. For the moment there is no specific therapy available and it has become a priority to develop novel rational therapeutic strategies based on new pathophysiological mechanisms. LÄS MER

  5. 4. A multifactorial approach to targeting signalling pathways in diabetic foot ulcers

    Författare :Sampath Kumar Narayanan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetic foot ulcers (DFU) are one of the most debilitating complication of diabetes that adversely impacts the health, economics and quality of life of the afflicted individual. The primary pathogenic factor of DFU is hyperglycemia, and its negative effects on normal signaling pathways is still being investigated. LÄS MER

  7. 5. In vitro studies of the diabetic condition using cultured fibroblasts with focus on wound healing

    Författare :Karin M Hehenberger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :diabetes; fibroblasts; wound healing; proliferation; protein kinaseC; lactate; growth factors; resistance.;

    Sammanfattning : This thesis focuses on the diabetic condition at the cellular level, and how this may lead to late complications. Defect wound healing in diabetic patients is poorly understood, but impaired granulation is observed clinically. We have therefore decided to study an in vitro system using cultured fibroblasts. LÄS MER