Sökning: "trigger factor"

Visar resultat 21 - 25 av 120 avhandlingar innehållade orden trigger factor.

  1. 21. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects

    Författare :Elena V. Ivanova; Kerstin Iverfeldt; Boris Zhivotovsky; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; apoptosis; caspase; local caspase activation; neurodegeneration; tau-anchored FRET sensors; tAFS; cancer; neuroblastoma; TNF-related apoptosis inducing ligand; TRAIL; protein kinase C; PKC; X-linked inhibitor of apoptosis protein; XIAP; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. LÄS MER

  3. 22. The Mechanism of translation termination in Escherichia coli

    Författare :David V. Freistroffer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Protein synthesis in E. coli is terminated by the release factors (RFs) and the ribosome is prepared for another round of protein synthesis by ribosome recycling factor (RRF), elongation factor G (EF-G) and initiation factor (IF3). LÄS MER

  4. 23. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'

    Författare :Marie Fischer; Gunnar Nilsson; Gunilla Enblad; Tor Olofsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Hodgkin lymphoma; mast cells; CD30; CD30L; IL-9; CCL5; atopic dermatitis; psoriasis; IL-8; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. LÄS MER

  5. 24. Experimental autoimmune sialadenitis : studies of immunopathogenesis, cellular signaling and MHC genetics

    Författare :Elwaleed Ibrahim Mustafa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune sialadenitis (EAS), an animal model for Sjogren´s syndrome (SS) in humans, develops spontaneously in certain mouse strains. A major feature of EAS and SS is infiltration of exocrine glands by mononuclear cells (MNC), and functional impairment of predominantly salivary and lachrymal glands leading to mouth and eye dryness. LÄS MER

  7. 25. Angiogenesis in human renal cell carcinoma : hypoxia, vascularity and prognosis

    Författare :Johanna Sandlund; Torgny Rasmuson; Börje Ljungberg; Kjell Grankvist; Anders Bergh; Elisabeth Kjellén; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endoglin CD105; CD31; prognosis; CA IX; HIF-2α; renal cell carcinoma; tissue microarray; immunohistochemistry; real-time PCR; stage; grade; Oncology; Onkologi;

    Sammanfattning : Background: Angiogenesis is recognised as a critical step in tumour progression. The angiogenic switch is activated by various trigger signals, such as hypoxia, low pH, and genetic mutations. Renal cell carcinoma (RCC) is often an aggressive tumour, and advanced disease has limited treatment options and bad prognosis. LÄS MER