Sökning: "skin cancer"

Visar resultat 1 - 5 av 239 avhandlingar innehållade orden skin cancer.

  1. 1. Tumors associated with Hereditary Nonpolyposis Colorectal Cancer: Defective Mismatch Repair and Familial Risk of Cancer

    Författare :Kajsa Ericson Lindquist; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; cancerology; Cytologi; onkologi; cancer; Multiple Tumors; Hereditary Nonpolyposis Colorectal Cancer; Cytology; Cohort study; Population based; Familial Risk of Cancer; Immunohistochemistry; MSH2; MSH6; MLH1; Microsatellite Instability; Soft Tissue Sarcomas; Cancer of the Upper Urinary Tract; Cancer of the Small Intestine; Colorectal Cancer;

    Sammanfattning : Inactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated sequences, and 90% of MSI tumors show loss of immunohistochemical expression for the MMR protein affected. LÄS MER

  2. 2. Cancer in organ transplant recipients

    Författare :Caroline Stenman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; organ transplantation; skin cancer; heart transplantation; lung transplantation;

    Sammanfattning : Tens of thousands of transplantations are performed around the world each year. Organ transplant recipients (OTR) are obliged to receive life-long medical treatment with immunosuppressive drugs to ensure graft function. However, such medications entail an increased risk of developing a broad spectrum of malignancies, especially skin cancer. LÄS MER

  3. 3. Diagnostic aspects of skin cancer and lichen sclerosus studied with laser scanning microscopy

    Författare :Despoina Kantere; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; skin cancer; lichen sclerosus; reflactance confocal microscopy; multiphoton microscopy;

    Sammanfattning : Histopathologic examination of tissue biopsies is the current gold standard for the diagnosis of dermatological problems. Similarly, in oncology, sentinel lymph node (SLN) biopsy is the state-of-the-art diagnostic method for me- tastasis screening. LÄS MER

  4. 4. Aspects of skin cancer diagnosis in clinical practice

    Författare :Ingela Ahnlide; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; skin cancer diagnosis; skin cancer; skin surgery; dermoscopy; basal cell carcinoma; squamous cell carcinoma; melanoma; dysplastic naevus; naevus; algorithms;

    Sammanfattning : Skin cancer incidence is increasing in fair-skinned populations. The three most common skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma (MM). A correct diagnosis is crucial for an efficient and tailored treatment for the skin cancer patient. LÄS MER

  5. 5. Invasion and Proliferation in Malignant Cells

    Författare :Sofie Svensson Månsson; Malmö Patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; breast cancer; squamous cell carcinoma; basal cell carcinoma; p16; proliferation; invasion; Cytologi; onkologi; cancer;

    Sammanfattning : Two key events in the oncogenic process of tumor cells are to acquire uncontrolled proliferation and invasive properties. This allows the tumor to grow and invade beyond the tissue from which the tumor cells originate. LÄS MER