Sökning: "screening methods"

Visar resultat 1 - 5 av 772 avhandlingar innehållade orden screening methods.

1. 1. Mass screening for celiac disease : a public health intervention from the participant perspective

   Författare :Katrina Nordyke; Anneli Ivarsson; Maria Emmelin; Lars Lindholm; David Grossman; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescents; celiac disease; children; EQ-5D; intervention; public health; narrative; screening; screening-detected; folkhälsa; Public health;

   Sammanfattning : Background  Celiac disease (CD) is a chronic disorder in genetically predisposed individuals in which damage to the small intestine is caused by eating foods containing gluten. The prevalence has been shown to vary from around 1-3%, but most people with CD are undiagnosed. LÄS MER

3. 2. Structure-Based Virtual Screening : New Methods and Applications in Infectious Diseases

   Författare :Micael Jacobsson; Anders Karlén; Mats Kihlén; Antti Poso; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; : drug discovery; docking; scoring; virtual screening; malaria; tuberculosis; Pharmaceutical chemistry; Läkemedelskemi;

   Sammanfattning : A drug discovery project typically starts with a pharmacological hypothesis: that the modulation of a specific molecular biological mechanism would be beneficial in the treatment of the targeted disease. In a small-molecule project, the next step is to identify hits, i.e. molecules that can effect this modulation. LÄS MER

4. 3. Computational Methods in Medicinal Chemistry : Mechanistic Investigations and Virtual Screening Development

   Författare :Fredrik Svensson; Christian Sköld; Anders Karlén; Anna Linusson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DFT; IRAP; Virtual Screening; Catalysis; Palladium; Medicinal Chemistry; Läkemedelskemi;

   Sammanfattning : Computational methods have become an integral part of drug development and can help bring new and better drugs to the market faster. The process of predicting the biological activity of large compound collections is known as virtual screening, and has been instrumental in the development of several drugs today in the market. LÄS MER

5. 4. Screening for Cardiovascular Risk and Diabetes in Primary Health Care : The Söderåkra Risk Factor Screening Study

   Författare :Ulla Petersson; Peter Nilsson; Carl Johan Östgren; Lars Brudin; Lars Weinehall; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Background: Cardiovascular disease (CVD) has been the predominant cause of morbidity and mortality for many decades in Sweden. Preventive work in primary health care through individual approach and community-based programmes has shown some success. LÄS MER

7. 5. Cervical screening with primary HPV : from research to clinical effectiveness

   Författare :Lovisa Bergengren; Gisela Helenius; Mats Karlsson; Matts Olovsson; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cervical cancer; screening; human papillomavirus HPV ; HPV prevalence; HPV genotypes; precancerous lesion; HSIL; self-sampling; postmenopausal women; health economy;

   Sammanfattning : Organized cervical screening has greatly reduced the incidence of cervical cancer where implemented. Human papilloma virus (HPV) is the cause of cervical cancer, and in later years, convincing evidence has led to cervical screening with HPV as the primary method being implemented around the world. LÄS MER