Sökning: "reservoir host"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden reservoir host.

  1. 1. MHC polymorphism and host-pathogen interactions: The case of Borrelia in its reservoir host, the bank vole Myodes glareolus

    Författare :Kristin Scherman; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Host-pathogen interaction; Negative frequency dependent selection; Myodes glareolus; Borrelia;

    Sammanfattning : The major histocompatibility complex (MHC) class IIB genes exhibit extensive allelic polymorphism, most likely maintained by pathogen-mediated balancing selection (PMBS). PMBS may operate in the form of heterozygote advantage (HA), and/or through the interaction of pathogens and specific MHC alleles via fluctuating selection (FS) or negative frequency-dependent selection (NFDS). LÄS MER

  2. 2. Biology of Borrelia garinii Spirochetes

    Författare :Pär Comstedt; Sven Bergström; Wolfram R. Zückert; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Borrelia garinii; Lyme borreliosis; birds; migration; reservoir host; complement; Ixodes ricinus; Europe; Asia; infection cycle; Molecular biology; Molekylärbiologi;

    Sammanfattning : Lyme borreliosis is a tick-transmitted infectious disease. The causative agents are spiral-shaped bacteria and the most common sign of infection is a skin rash at the site of the tick bite. LÄS MER

  3. 3. Viruses on the wing: evolution and dynamics of influenza A virus in the Mallard reservoir

    Författare :Michelle Wille; Jonas Waldenström; Timm Harder; Linnéuniversitetet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Co-infections; Ecology; Epidemiology; Evolution; Host-Parasite Interactions; Immunity; Influenza A Virus; Mallard; Phylogeny; Virology; Waterfowl; Wild Birds; Wildlife Disease; Zoonotisk ekologi; Zoonotic Ecology;

    Sammanfattning : This thesis explores the evolution of avian influenza A viruses (IAV), as well as host-pathogen interactions between these viruses and their main reservoir host, the Mallard (Anas platyrhynchos). IAV is a genetically diverse, multi-host virus and wild birds, particularly dabbling ducks, are the natural reservoir. LÄS MER

  4. 4. Invasive group A streptococcal infection : host and pathogen interactions

    Författare :Björn K.G. Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Group A streptococci; invasive infections; erysipelas; Streptococcal Toxic Shock Syndrome STSS ; epidemiology; M1 serotype streptococcal pyrogenic exotoxins Spe ; SpeA; toxin neutralization; opsonization;

    Sammanfattning : Invasive group A streptococcal (GAS) infections were studied in 229 patients with a clinical diagnosis of erysipelas and 151 patients with GAS bacteremia, respectively. Beta-hemolytic streptococci were identified in about a third of the erysipelas patients, mostly group A, whereas group G streptococci were identified in about half as many episodes. LÄS MER

  5. 5. Lifestyle and Genome Evolution in Vector-Borne Bacteria : A Comparison of Three Bartonella Species

    Författare :Anna Carolin Frank; Siv Andersson; Stewart Cole; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Biology; Bartonella; evolution; host-restriction; vector-borne; horizontal gene transfer; genome reduction; alpha-proteobacteria; Type-IV secretion; Biologi; Biology; Biologi;

    Sammanfattning : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. LÄS MER