Sökning: "FGF FGFR signalling"

Hittade 2 avhandlingar innehållade orden FGF FGFR signalling.

1. 1. The Role of Shb in Angiogenesis, FGF and VEGF Signalling in Endothelial Cells

   Författare :Kristina Holmqvist; Michael Welsh; Eva Degerman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Shb; Src; FAK; Angiogenesis; VEGFR-2; FGFR-1; Endothelial cells; Spreading; Stress fiber formation; siRNA; VEGF; FGF; Differentiation; Migration; Tube formation; RNAi; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Sammanfattning : Angiogenesis is defined as the formation of new capillary blood vessels from pre-existing ones. This process involves several steps including: migration, proliferation and differentiation of endothelial cells into blood vessels. LÄS MER

3. 2. Gene Expression in mESC Deficient in FGFR Signalling and the Identification of the Novel Gene Ened

   Författare :Renata Gustafsson; Muskelbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryonic stem cells; differentiation; FGF FGFR signalling; gene expression; microarray; Ened; early embryonic development;

   Sammanfattning : Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of blastocyst stage embryos, and upon differentiation into embryoid bodies (EBs) they recapitulate the genetic, cellular and morphological events occurring in early embryogenesis. Among several signalling pathways and inductive factors, the fibroblast growth factors (FGFs) and their receptors (FGFRs) have been shown to be important during early embryogenesis. LÄS MER