Sökning: "replicative ageing"

Hittade 3 avhandlingar innehållade orden replicative ageing.

  1. 1. Mathematical Modelling of Cellular Ageing: a Multi-Scale Perspective

    Författare :Barbara Schnitzer; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; replicative ageing; healthy ageing; yeast; complex systems; multi-scale model; hybrid model; flux balance analysis; ordinary differential equations; Boolean modelling;

    Sammanfattning : In a growing and increasingly older population, we are progressively challenged by the impact of ageing on individuals and society. The UN declared the years 2021-2030 as the Decade of Healthy Ageing, highlighting the efforts to minimise the burden of ageing and age-related diseases. LÄS MER

  3. 2. The construction, analysis and validation of mechanistic mathematical models of protein kinetics in the context of replicative ageing in budding yeast

    Författare :Johannes Borgqvist; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Protein kinetics; Replicative ageing; Cdc42; Ordinary differential equations; Reaction diffusion models; Parameter estimation; Model validation; Model construction; Symmetry methods;

    Sammanfattning : Mathematical modelling constitutes a forceful tool for elucidating properties of biological systems. Using theoretical approaches in combination with experimental techniques it is possible to study specific molecular aspects of phenomena such as the ageing of human beings. LÄS MER

  4. 3. Studies of molecular mechanisms of telomere maintenance in Naumovozyma castellii

    Författare :Ahu Karademir Andersson; Molekylär cellbiologi; []
    Nyckelord :YEAST; Saccharomyces castellii; Naumovozyma castellii; Processvity; Telomerase; Telomere; ALT; Strain engineering;

    Sammanfattning : Telomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins. LÄS MER