Sökning: "complete linkage"
Visar resultat 1 - 5 av 36 avhandlingar innehållade orden complete linkage.
Sammanfattning : In recent years, a revolution in the development of new techniques have made it possible to perform genetic studies of inherited disorders without prior knowledge about the gene product or the function of the gene. The techniques include linkage studies, allelic association studies, physical mapping and the sequencing of candidate genes for finding disease causing mutations. LÄS MER
2. Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications
Sammanfattning : In linkage analysis or, in a wider sense, gene mapping one searches for disease loci along a genome. This is done by observing so called marker genotypes (alleles) and phenotypes (affecteds/unaffecteds) of a pedigree set, i.e. LÄS MER
Sammanfattning : In this thesis we study efficient computational methods for geometrical problems of practical importance and theoretical interest. The problems that we consider are primarily complete linkage clustering, minimum spanning trees, and approximating minimum weight triangulation. Below is a list of the main results proved in the thesis. LÄS MER
Sammanfattning : Pain is a major public health issue throughout the world. Increased understanding of the different forms of pain and identification of susceptibility genes could contribute to improved treatments. LÄS MER
Sammanfattning : The dog was the first animal to be domesticated and the process started at least 15 000 years ago. Today it is the most morphologically diverse mammal, with a huge variation in size and shape. LÄS MER