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Visar resultat 11 - 15 av 19 avhandlingar som matchar ovanstående sökkriterier.

  1. 11. The ADAPT scaffold as a tool for diagnostic imaging and targeted therapy

    Författare :Emma von Witting; Sophia Hober; Inger Sandlie; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein G; ABD; ADAPT; affinity proteins; antibody; protein engineering; targeted therapy; nuclear medicine; molecular imaging; HER2; radionuclide therapy; Bioteknologi; Biotechnology;

    Sammanfattning : Molecular recognition, or the specific interactions between a protein and its ligand, is central to biology and a key factor for many different clinical and technical applications. Despite antibodies being only one of many different affinity proteins, it has by far been the most successful. LÄS MER

  3. 12. PNA and affinity protein tools for selective tumor targeting of radiopharmaceuticals

    Författare :Hanna Tano; Amelie Eriksson Karlström; Per-Åke Nygren; Dario Neri; KTH; []
    Nyckelord :Cancer therapy; targeted radionuclide therapy; affinity proteins; Affibody molecules; CD38; GRPR; HER2; nanobody; peptide; PNA; RM26; pretargeting; Cancerterapi; radionuklid terapi; affinitetsproteiner; affibody molekyler; CD38; GRPR; HER2; nanobody; peptid; PNA; RM26; pretargeting; Biotechnology; Bioteknologi;

    Sammanfattning : Targeted radiotherapy of cancer intends to selectively deliver cytotoxic radionuclides to tumor cells. Affinity proteins of various kinds are explored for this task, and depending on the affinity protein used, different challenges arise. LÄS MER

  4. 13. Influence of metallic fission products and self irradiation on the rate of spent nuclear fuel-matrix dissolution

    Författare :Sara Nilsson; Mats Jonsson; István Furó; Göran Lindbergh; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear chemistry; Kärnkemi;

    Sammanfattning : Denna licentiatavhandling behandlar effekten av två inneboende egenskaper (fissions produkter och egenbestrålning) hos utbränt kärnbränsle på hastigheten för strålningsinducerad upplösning av bränslematris (UO2). I ett framtida djupförvar kommer det utbrända kärnbränslet att deponeras 500 meter ner i berggrunden i en reducerande miljö. LÄS MER

  5. 14. Stability of Alternative Nuclear Fuel Materials in Aqueous Systems

    Författare :Sawsan El Jamal; Mats Jonsson; Mats Johnsson; Claire Corkhill; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; UC; UN; UO2; gamma radiolysis; oxidative dissolution; H2O2; studtite; additive; UC; UN; UO2; gammaradiolys; oxidativ upplösning; H2O2; studtite; additiv; Kemi; Chemistry;

    Sammanfattning : Nuclear power produces a large portion of the electricity worldwide. It has been the largest low-carbon energy source for more than 30 years and has played an essential role in the security of energy supplies for many countries. LÄS MER

  7. 15. Computational and experimental methods for imaging and dosimetry in 177Lu radionuclide therapy : Classical and novel gamma cameras

    Författare :Daniel Roth; Lund Medicinsk strålningsfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radionuklidterapi; [177Lu]Lu-DOTA-TATE; Gammakamera; Aktivitetskvantifiering; Dosimetri; CdZnTe; Monte Carlo; Radionuclide therapy; [177Lu]Lu-DOTA-TATE; Gamma camera imaging; Activity quantification; Dosimetry; CdZnTe; Monte Carlo;

    Sammanfattning : Radionuclide therapy (RNT) is a form of radiotherapy that uses unsealed radioactive sources for the delivery of ionising radiation within a patient's body.Radiation dosimetry is not used routinely in all centres, and the RNT field can benefit from more data on pharmacokinetics and absorbed doses (ADs). LÄS MER