Sökning: "radiation therapy treatment planning"

Visar resultat 11 - 15 av 65 avhandlingar innehållade orden radiation therapy treatment planning.

  1. 11. High Performance Computing for the Optimization of Radiation Therapy Treatment Plans

    Författare :Felix Liu; Stefano Markidis; Artur Podobas; Albin Fredriksson; David Keyes; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HPC; Radiation Therapy; Optimization; Numerical Linear Algebra; Interior Point Methods; Datalogi; Computer Science;

    Sammanfattning : Radiation therapy is a clinical field in which computer simulations play a crucial role. Before patients undergo radiation therapy, an individual treatment plan for each patient needs to be created based on the specifics of their case (a process often referred to as \emph{treatment planning}). LÄS MER

  2. 12. Robust optimization of radiation therapy accounting for geometric uncertainty

    Författare :Albin Fredriksson; Anders Forsgren; Timothy C. Y. Chan; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; intensity-modulated proton therapy; uncertainty; robust planning; setup error; range error; intensity-modulated radiation therapy; multicriteria optimization;

    Sammanfattning : Geometric errors may compromise the quality of radiation therapy treatments. Optimization methods that account for errors can reduce their effects.The first paper of this thesis introduces minimax optimization to account for systematic range and setup errors in intensity-modulated proton therapy. LÄS MER

  3. 13. 177Lu-DOTA-octreotate Radionuclide Therapy of Neuroendocrine Tumours : Dosimetry-Based Therapy Planning and Outcome

    Författare :Ulrike Garske-Román; Barbro Eriksson; Anders Sundin; Jens Sörensen; Dik Kwekkeboom; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : Peptide receptor radionuclide therapy for the internal radiation of neuroendocrine tumours expressing somatostatin receptors has made great advances and offers promising results. 177Lu-DOTA-octreotate is one of the most widely used radiopeptides, but kidneys and bone marrow are organs at risk. LÄS MER

  4. 14. Probabilistic machine learning methods for automated radiation therapy treatment planning

    Författare :Tianfang Zhang; Jimmy Olsson; Steve Jiang; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Matematisk statistik; Mathematical Statistics;

    Sammanfattning : In this thesis, different parts of an automated process for radiation therapy treatment planning are investigated from a mathematical and computational perspective. Whereas traditional inverse planning is labor-intensive, often comprising several reiterations between treatment planner and physician before a plan can be approved, much of recent research have been aimed at using a data-driven approach by learning from historically delivered plans. LÄS MER

  5. 15. Radioiodine Therapy of Hyperthyroidism - Simplified patient-specific absorbed dose planning

    Författare :Helene Jönsson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Radiofarmaceutisk teknik; Radiopharmaceutical technology; absorbed dose. optimise; hyperthyroidism; therapy; 131-I; radioiodine; Nukleärmedicin; radiobiology; Nuclear medicine;

    Sammanfattning : Radioiodine therapy of hyperthyroidism is the most frequently performed radiopharmaceutical therapy. To calculate the activity of 131-I to be administered for giving a certain absorbed dose to the thyroid, the mass of the thyroid and the individual biokinetic data, normally in the form of uptake and biologic half-time, have to be determined. LÄS MER