Sökning: "pyrophosphate"

Visar resultat 11 - 15 av 35 avhandlingar innehållade ordet pyrophosphate.

  1. 11. Targeting cell envelope synthesis of Streptococcus pneumoniae and microfluidic diagnostic tool development

    Författare :Elisabeth Reithuber; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Evolving antibiotic resistance warrants the development of new therapeutic and diagnostic approaches as part of the strategies to secure future antibacterial therapies and preserve the compounds currently available. Work constituting the thesis characterized small molecules yielded from a screen for autolysis inducing compounds on Streptococcus pneumoniae. LÄS MER

  3. 12. The proton pumping inorganic pyrophosphatase from Rhodospirillum rubrum

    Författare :Pål Nyrén; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The aim of the present investigation was to study the mechanism by which light-energy is transformed to biologically useful chemical-energy in the form of inorganic pyrophosphate (PPi). The study was performed on chromatophores (subcellular membrane structures) from the photosynthetic nonsulphur bacterium Rhodospiri Hum rubrum. LÄS MER

  4. 13. Homotrimeric dUTPases : Principles of Catalysis and Inhibitor Design

    Författare :Lorena Gonzalez Palmén; Jan Kvassman; Dolores Gonzalez-Pacanowska; Högskolan i Kalmar; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dUTPases; kinetics; ground state destabilization; inhibitors; Biochemistry; Biokemi; Natural Science; Naturvetenskap;

    Sammanfattning : The ubiquitous enzyme dUTPase hydrolyzes dUTP into dUMP and pyrophosphate, preventing DNA fragmentation and cell death due to accumulation of dUTP. Inhibitors of dUTPase could serve as drugs in the treatment of cancers and infectious diseases. This thesis presents five studies. LÄS MER

  5. 14. Recombinant Enzymes in Pyrosequencing Technology

    Författare :Nader Nourizad; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; apyrase; pyrosequencing; pichia pastoris; protein expression; fusion protein; luciferase; DNA template; clone checking; DNA polymerase;

    Sammanfattning : Pyrosequencing is a DNA sequencing method based on thedetection of released pyrophosphate (PPi) during DNA synthesis.In a cascade of enzymatic reactions, visible light isgenerated, which is proportional to the number of nucleotidesincorporated into the DNA template. When dNTP(s) areincorporated into the DNA template, inorganic PPi is released. LÄS MER

  7. 15. Iron based Li-ion insertion materials for battery applications

    Författare :Andreas Blidberg; Fredrik Björefors; Mats Johnsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Li-ion; battery; Li2FeP2O7; LiFeSO4F; PEDOT; Chemistry with specialization in Inorganic Chemistry; Kemi med inriktning mot oorganisk kemi;

    Sammanfattning : Li-ion batteries are currently the most efficient technology available for electrochemical energy storage. The technology has revolutionized the portable electronics market and is becoming a corner stone for large scale applications, such as electric vehicles. LÄS MER