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Visar resultat 1 - 5 av 35 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. The biological and physical performance of high strength dicalcium phosphate cement in physiologically relevant models

    Författare :Michael Pujari-Palmer; Håkan Engqvist; Marjam Karlsson Ott; Christele Combes; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biomaterial; bioceramic; osteoinduction; calcium phosphate; cement; osteoblast; pyrophosphate; Rebamipide; drug delivery; screw augmentation; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

    Sammanfattning : The chemical properties of calcium phosphate cements (CPCs) are very similar to the mineral phase of bone. CPCs are, consequently, very effective substrates (scaffolds) for tissue engineering; bone and stem cells attach readily, and can proliferate and differentiate to form new bone tissue. LÄS MER

  2. 2. Insights into the metabolism of Clostridium thermocellum for cellulosic ethanol production

    Författare :Johannes Yayo; Antonius J. A. van Maris; Richard Sparling; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Clostridium thermocellum; ethanol; glucose; fructose; amino acids; pyrophosphate; chaotropicity; thermodynamic driving force; laboratory evolution; chemostats; metabolic engineering; Biotechnology; Bioteknologi;

    Sammanfattning : The societal goal of reaching net-zero CO2 emissions requires development of integrated biorefineries to produce biomass-derived fuels and chemicals. For sustainable second-generation bioethanol production, consolidated bioprocessing with the thermophile Clostridium thermocellum is regarded as a promising concept in view of the microorganism’s native ability to efficiently degrade plant cell wall material. LÄS MER

  3. 3. Analysis and engineering of central metabolism in Clostridium thermocellum

    Författare :Teun Kuil; Antonius J. A. van Maris; Ruud Weusthuis; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Clostridium thermocellum; biofuels; ethanol; atypical glycolysis; pyrophosphate; phosphofructokinase; thermodynamic driving force; redox cofactor balancing; amino acid secretion; chaotropicity; hexose utilization; laboratory evolution; metabolic engineering; Biotechnology; Bioteknologi;

    Sammanfattning : To mitigate climate change, greenhouse gas emissions must be reduced to net-zero in 2050 requiring a drastic transition in today´s energy sector. To achieve this goal, the use of biofuels produced from lignocellulosic feedstocks, including agricultural and forestry residues, is expected to play an important role. LÄS MER

  4. 4. Cloning, expression and mutagenesis of the gene encoding the proton-pumping inorganic pyrophosphatase from Rhodospirillum rubrum : studies on pyrophosphate hydrolysis and electrogenic proton-translocation

    Författare :Anders Schultz; Baz Jackson; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : .... LÄS MER

  5. 5. Advancements in Firefly Luciferase-Based Assays and Pyrosequencing Technology

    Författare :Jonas Eriksson; KTH; []
    Nyckelord :bioluminescence; osmolytes; glycine betaine; thermostability; firefly luciferase; inorganic pyrophosphatase; inorganic pyrophosphate; Pyrosequencing technology; secondary DNA-structures; Sequenase; Klenow-polymerase; reaction rates; temperature;

    Sammanfattning : Pyrosequencing is a new DNA sequencing method relying on thesequencing-by-synthesis principle and bioluminometric detectionof nucleotide incorporation events. The objective of thisthesis was improvement of the Pyrosequencing method byincreasing the thermal stability of firefly luciferase, and byintroducing an alternative DNA polymerase and a new nucleotideanalog. LÄS MER