Sökning: "provocation"

Visar resultat 16 - 20 av 127 avhandlingar innehållade ordet provocation.

1. 16. Evaluation of hand skin temperature : Infrared thermography in combination with cold stress tests

   Författare :Katarina Leijon Sundqvist; Niklas Lehto; James Mercer; Luleå tekniska universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cold provocation; rewarming; thermoregulation; dynamic IR thermography; Health Science; Hälsovetenskap;

   Sammanfattning : AbstractSince ancient times, warm or cold skin on the human body has been used as a parameter in evaluating health. Changes in body temperature are attributed to diseases or disorders. The assessment of body temperature is often performed to measure fever by detecting an elevated core temperature. LÄS MER

3. 17. Mechanism-Based Modeling of the Glucose-Insulin Regulation during Clinical Provocation Experiments

   Författare :Petra Jauslin-Stetina; Mats Karlsson; Nicolas Frey; Philippe Jacqmin; Uppsala universitet; []
   Nyckelord :Pharmacokinetics Pharmacotherapy; Glucose homeostasis; Type 2 diabetes; IVGTT; OGTT; Meal test; Circadian variation; Mechanism-based; NONMEM; Farmakokinetik Farmakoterapi;

   Sammanfattning : Type 2 diabetes is a complex chronic metabolic disorder characterized by hyperglycemia associated with a relative deficiency of insulin secretion and a reduced response of target tissues to insulin. Considerable efforts have been put into the development of models describing the glucose-insulin system. LÄS MER

4. 18. Immunotherapy of children with rhinoconjunctivitis due to birch pollinosis

   Författare :Christian Möller; Umeå universitet; []
   Nyckelord :Birch pollinosis; Conjunctival provocation test; Crossed radioimmunoelectrophoresis; Crossreactivity tree pollens; Immunotherapy; Oral immunotherapy; Polyethyleneglycol absorption; Pollen counts; Rhinoconjunctivitis; Symptom score;

   Sammanfattning : In this investigation of immunotherapy (IT) children 6-16 years old with rhinoconjunctivitis due to birch polli­nosis were included.I. Methodological studies. To monitor IT a reliable provocation test is desirable. LÄS MER

5. 19. Pharmacometrics Modelling in Type 2 Diabetes Mellitus : Implications on Study Design and Diabetes Disease Progression

   Författare :Siti Maisharah Sheikh Ghadzi; Maria C. Kjellsson; Mats O. Karlsson; Sandra Visser; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometric; type 2 diabetes mellitus; impaired glucose tolerance; prediabetes; anti-diabetes drug development; insulin; glucose; natural diabetes disease progression; lifestyle intervention; short-term provocation; long-term effect; glucose homeostasis; glucose and insulin regulation; weight; dropout; Pharmaceutical Science; Farmaceutisk vetenskap; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

   Sammanfattning : Pharmacometric modelling is widely used in many aspects related to type 2 diabetes mellitus (T2DM), for instance in the anti-diabetes drug development, and in quantifying the disease progression of T2DM.The aim of this thesis were to improve the design of early phase anti-diabetes drug development studies with the focus on the power to identify mechanism of drug action (MoA), and to characterize and quantify the progression from prediabetes to overt diabetes, both the natural progression and the progression with diet and exercise interventions, using pharmacometrics modelling. LÄS MER

7. 20. Clinical and experimental studies in nickel allergy

   Författare :Monica Hindsén; Dermatologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nickel absorption; Nickel; allergic contact dermatitis; patch test reactivity; flare-up reactions; oral nickel provocation; previous contact dermatitis; hand eczema; atopy; Dermatology; venereology; Dermatologi; venereologi;

   Sammanfattning : Kliniska och experimentella studier av nickelallergi Nickelallergi är vanligt, särskilt hos kvinnor. Nickelallergi leder ofta till periodiskt eller kroniskt eksem, främst på händerna. Dessa eksem kan vara svårläkta och leda till långa sjukskrivningsperioder. LÄS MER