Sökning: "protein reconstitution"

Visar resultat 21 - 25 av 46 avhandlingar innehållade orden protein reconstitution.

  1. 21. Reconstitution of Membrane-Bound Enzymes for Neutron Scattering Studies: A Case Study of Human Dihydroorotate Dehydrogenase

    Författare :Manuel Orozco; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane proteins; dihydroorotate dehydrogenase; pyrimidine metabolism; neutron scattering; ubiquinone; QCM-D;

    Sammanfattning : Membrane proteins are challenging to study due the necessity to maintain a lipid-like environment to preserve their structure and function. Particularly difficult to study are membrane-bound enzymes that interact with lipophilic substrates. LÄS MER

  3. 22. The role of the mitochondrial membrane system in apoptosis : the influence of oxidative stress on membranes and their interactions with apoptosis-regulating Bcl-2 proteins

    Författare :Martin Lidman; Gerhard Gröbner; Magnus Wolf-Watz; Philip Williamson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bax; Bc-2; apoptosis; mitochondria; membranes; oxidized lipids; NMR; calorimetry; circular dichroism; biokemi; Biochemistry; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : Apoptosis is a crucial process in multicellular organisms in sculpting them, especially during embryogenesis. In addition, apoptosis is responsible for the clearance of harmful or damaged cells which can otherwise be detrimental to the organism. LÄS MER

  4. 23. Structural analysis of microsomal glutathione transferase 1 by electron crystallography

    Författare :Ingeborg Schmidt-Krey; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The goals of this project were the two-dimensional crystallization of the membrane protein microsomal glutathione transferase 1 and the three-dimensional structure determination by electron crystallography. Microsomal glutathione transferase 1 is a homotrimeric membrane protein. LÄS MER

  5. 24. Characterization of the structure and function of the Pho84 high-affinity phosphate transporter of Saccharomyces cerevisiae

    Författare :Ulrika Fristedt; Gerard Leblanc; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : All living organisms, from bacteria and yeast to mammalian cells, must respond to a fluctuating extracellular environment. Information contained in such fluctuations is signaled via the cell surface to the interior of the cell, resulting in responses such as altered gene expression and protein activity. LÄS MER

  7. 25. Role of Wnt-5a in breast cancer

    Författare :Janna Sand-Dejmek; Malmö Experimentell patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; signal transduction; metastasis; adhesion; breast cancer; Syk; Wnt-5a; DDR1; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Sammanfattning : Breast cancer is one of the most common cancer forms in the industrialized world. Only in Sweden, nearly 6000 women are diagnosed with breast cancer each year and 1/3 of them eventually succumb to the disease. LÄS MER