Sökning: "protein orientation"
Visar resultat 1 - 5 av 96 avhandlingar innehållade orden protein orientation.
1. Molecular principles of protein stability and protein-protein interactions
Sammanfattning : Proteins with highly specific binding properties constitute the basis for many important applications in biotechnology and medicine. Immunoglobulins have so far been the obvious choice but recent advances in protein engineering have provided several novel constructs that indeed challenge antibodies. LÄS MER
2. Structural and thermodynamical basis for molecular recognition between engineered binding proteins
Sammanfattning : The structural determination of interacting proteins, both as individual proteins and in their complex, complemented by thermodynamical studies are vital in order to gain in-depth insights of the phenomena leading to the highly selective protein-protein interactions characteristic of numerous life processes. This thesis describes an investigation of the structural and thermodynamical basis for molecular recognition in two different protein-protein complexes, formed between so-called affibody proteins and their respective targets. LÄS MER
3. Cell-protein-material Interactions on Bioceramics and Model Surfaces
Sammanfattning : The objective of this thesis was to investigate and characterize the interaction between blood proteins and different surfaces with emphasis on protein adsorption to bioceramics and model surfaces. Special effort was made to monitor the spontaneous and selective adsorption of proteins from human plasma and to examine the orientation, conformation and functional behavior of single proteins after adsorption. LÄS MER
4. Biosensor surface chemistry for oriented protein immobilization and biochip patterning
Sammanfattning : This licentiate thesis is focused on two methods for protein immobilization to biosensor surfaces for future applications in protein microarray formats. The common denominator is a surface chemistry based on a gold substrate with a self-assembled monolayer (SAM) of functionalized alkanethiolates. LÄS MER
5. Interactions between Wood Polymers in Wood Cell Walls and Cellulose/Hemicellulose Biocomposites
Sammanfattning : A wood fibre is a complex multi component biocomposite that is hierarchically organised. The arrangement of a wood fibre on the ultrastructural level is highlycontrolled by the interactions between the main structural polymers, i.e. cellulose, various hemicelluloses and lignin, as well as in some parts also pectin and protein. LÄS MER