Sökning: "peter martin"

Visar resultat 16 - 20 av 83 avhandlingar innehållade orden peter martin.

  1. 16. Preclinical and Clinical Development of the Novel Cyanoguanidine CHS 828 for Cancer Treatment

    Författare :Peter Hovstadius; Rolf Larsson; Elin Lindhagen; Martin Höglund; Sigurd Vitols; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical drug development; CHS 828; Cyanoguanidines; Oncology; Clinical Drug Development; Klinisk läkemedelsutveckling; Pharmaceutical chemistry; Läkemedelskemi;

    Sammanfattning : CHS 828 is a cyanoguanidine with anti-tumour properties which has shown promising effects in several preclinical models. This thesis describes both preclinical and clinical studies aiming to investigate disease specific activity, clinical tolerability and efficacy of CHS 828. LÄS MER

  3. 17. Functions of Generalized Bounded Variation

    Författare :Martin Lind; Viktor Kolyada; Peter Oswald; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bounded p-variation; generalized bounded variation; modulus of continuity; function spaces; embeddings; Matematik; Mathematics;

    Sammanfattning : This thesis is devoted to the study of different generalizations of the classical conception of a function of bounded variation.First, we study the functions of bounded p-variation introduced by Wiener in 1924. We obtain estimates of the total p-variation (1.. LÄS MER

  4. 18. Macrolide Antibiotics in Bacterial Protein Synthesis

    Författare :Martin Lovmar; Måns Ehrenberg; Tanel Tenson; Peter B. Moore; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; protein synthesis; macrolides; resistance; initiation of translation; non-competitive inhibitors; kinetics; translation accuracy; proof-reading; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Macrolides are a large group of clinically relevant antibiotics that inhibit protein synthesis by binding to the large ribosomal subunit in the peptide exit tunnel, close to the peptidyl transferase center (PTC). We have shown that the peptide length of the resulting peptidyl-tRNA drop-off products is proportional to the distance between the PTC and the respective macrolide in the tunnel. LÄS MER

  5. 19. Diffusive properties of granitic rock as measured by in-situ electrical methods

    Författare :Martin Löfgren; Ivers Neretnieks; Peter Vilks; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical engineering; Kemiteknik; Chemical engineering; Kemiteknik;

    Sammanfattning : Diffusion into the rock matrix has been identified as one of the most important retention mechanisms for dissolved contaminants in fractured crystalline rock. In this thesis the diffusive properties of granitic rock, described by the formation factor, have been investigated by electrical methods. LÄS MER

  7. 20. What do students’ feel about mathematics? : Compulsory school students’ emotions and motivation towards mathematics

    Författare :Martin Nyman; Lovisa Sumpter; Kerstin Larsson; Peter Liljedahl; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Motivation; Emotion; Feelings; Primary education; Compulsory education; Motivation; Känslor; Grundskola; Grundskolelever; matematikämnets didaktik; Mathematics Education;

    Sammanfattning : This licentiate thesis deals with compulsory school students’ expressed emotions and motivation towards mathematics. Theoretically, it has been guided by Hannula’s meta-theory on affect (e.g., 2012), of which emotion and motivation are part. LÄS MER