Sökning: "pascal"

Visar resultat 1 - 5 av 48 avhandlingar innehållade ordet pascal.

  1. 1. Elucidating causal relationships between energy homeostasis and cardiometabolic outcomes

    Författare :Pascal Mutie; Genetisk och molekylär epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adiposity; causal inference; Cardiometabolic disease; Mendelian randomization;

    Sammanfattning : Energy metabolism dyshomeostasis is associated with multiple health problems. For example, abundant epidemiological data show that obesity and overweight increase the risk of cardiometabolic diseases and early mortality. LÄS MER

  3. 2. Cancer vaccine strategies and studies of human thioredoxin reductase splice variants

    Författare :Pascal Dammeyer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cancer involves abnormal, uncontrolled proliferation of cells, and evasion from the immune system. Immune evasion can be caused by defects in one or more of the components of the major histocompatibility complex class I antigen machinery, e.g. the beta2-microglobulin (beta2m) molecule. LÄS MER

  4. 3. Molecular and cellular strategies to enhance efficacy of T cell-based cancer therapy

    Författare :Pascal Dammeyer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :β2-microglobulin; MHC class I antigen defects; immune escape; heal-inducible; amplifier vector; GM-CSF; tumor immunity; T lymphocytes;

    Sammanfattning : A combined approach of vaccination with β2-microglobulin (β2m)-deficient dendritic cells (DCs) and granulocyte-macrophage colony-stimulating factor (GM-CSF) as a potent adjuvant may link cellular and molecular strategies to further enhance anti-tumor T-cell responses. T lymphocytes can mediate a potent anti-tumor immune response. LÄS MER

  5. 4. Sex chromosomes in willows : evolutionary studies of the ZW sex chromosome system in Salix viminalis

    Författare :Pascal Pucholt; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Sexual reproduction is found in most eukaryotes and has in the majority of animal species led to the evolution of separate sexes. In contrast, only 5-6% of all angiospersms are dioecious with female and male flowers on separate individuals. Interestingly, dioecy has evolved hundreds of times independently and at different timepoints in angiosperms. LÄS MER

  7. 5. Electroremediation of contaminated soil

    Författare :Pascal Suèr; Bert Allard; Lisbeth M. Ottosen; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; electrokinetic remediation; contaminated soil; mercury; heavy metals; organic compounds; Chemistry; Kemi; Enviromental Science; Miljövetenskap;

    Sammanfattning : Electroremediation was applied to contaminated soils in order to study the transport of metals and organic compounds by the external electric field. The electric field caused acidic conditions near the anode, so that copper, zinc, lead, nickel, cadmium, calcium and manganese were released from soil from a chlor-alkali site. LÄS MER