Sökning: "oxidized LDL"

Visar resultat 31 - 35 av 48 avhandlingar innehållade orden oxidized LDL.

1. 31. Novel and Traditional Risk Factors for Coronary Artery Disease : Role of Coronary Artery Calcium, Lipidomics, Psychosocial Factors and Diet

   Författare :Demir Djekic; Ole Fröbert; Annika Rosengren; Tuulia Hyötyläinen; Anna M. Nordenskjöld; Magnus Bäck; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Novel risk factors; coronary artery calcium; lipidomics; lipidome; psychosocial factors; vegetarian diet; gut microbiota; metabolome;

   Sammanfattning : Background: The aim of the research reported in this thesis was to determine the association of novel and traditional risk factors with coronary artery calcium (CAC), a marker of subclinical coronary artery disease (CAD) in healthy individuals. In addition, we investigated the effects of a vegetarian, compared to a meat diet, on novel and traditional risk factors in patients with diagnosed CAD. LÄS MER

3. 32. Endothelium-Dependent Vasodilation and Oxidative Stress in Chronic Renal Failure

   Författare :Margus Annuk; Ola Samuelson; Uppsala universitet; []
   Nyckelord :Medical sciences; endothelium; oxidative stress; chronic renal failure; L-arginine; diclofenac; erythropoietin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Internal Medicine; invärtesmedicin;

   Sammanfattning : Cardiovascular disease (CVD) is the major cause of death in patients with chronic renal failure (CRF). Endothelial function and oxidative stress (OS) have previously been shown to be important in the pathogenesis of CVD. In this thesis, the endothelium-dependent vasodilatation (EDV) and OS were investigated in the patients with CRF. LÄS MER

4. 33. Expression profiling of human macrophages and atherosclerotic plaques to identify genes and mechanisms that modulate the development of atherosclerosis

   Författare :Daniel Hägg; Göteborgs universitet; []
   Nyckelord :;

   Sammanfattning : Macrophages play an important role in atherosclerosis, a disease that affects large and medium size arteries and causes clinical manifestations such as myocardial infarction or stroke. The aim of this thesis was to identify genes that are important in the development of atherosclerosis. LÄS MER

5. 34. Immune mechanisms in atherosclerotic vascular disease

   Författare :Jasmina Cvetkovic; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Atherosclerosis; rheumatoid arthritis; stroke; autoantibodies; pro-inflammatory cytokines;

   Sammanfattning : Atherosclerosis has been categorized as an inflammatory disorder, with similar chronic inflammatory conditions found in rheumatoid arthritis. It entails an unregulated accumulation of lipids in the vessel wall, which leads to the development of cardiovascular diseases. LÄS MER

7. 35. Immune mechanisms in atherosclerosis : the role of T cells in murine models of atherosclerosis

   Författare :Xinghua Zhou; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :atherosclerosis; inflammation; murine models; low density lipoprotein; lipoprotein oxidation; T lymphocyte; T-cell antigen receptors; hypercholesterolemia; autoantibodies; T-cell cytokines; immunization; cardiolipin;

   Sammanfattning : Atherosclerosis is an inflammatory disease. Much interest has been focused on the immune responses in the pathogenesis of the disease. The role of T cells in the development of atherosclerosis was therefore investigated in murine models in this study. LÄS MER