Sökning: "T-cell antigen receptors"

Visar resultat 1 - 5 av 95 avhandlingar innehållade orden T-cell antigen receptors.

1. 1. Early events in T cell development

   Författare :Karin Leandersson; Malmö Cancerimmunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; pTalpha; gammadelta T cell; alphabeta T cell; development; thymus; thymocyte; serology; transplantation; Immunologi; serologi;

   Sammanfattning : T cells constitute a heterogenous population of lymphocytes. Their unifying property is that they express surface bound antigen-receptors, called T cell receptors (TCRs). The TCR is a heterodimer composed of either TCRalpha and beta chain proteins (alphabeta TCR) or gamma and delta chain proteins (gammadelta TCR). LÄS MER

3. 2. Smoking and T cell co-stimulation in rheumatoid arthritis

   Författare :Caroline Wasén; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; CD8 T cell; programmed cell death-1; programmed cell death-1 ligand 1; smoking; microRNA;

   Sammanfattning : In this thesis I investigated if smoking limits the co-stimulatory system of CD8+ T cells in rheumatoid arthritis (RA). I took special interest in the co-inhibitory receptor PD-1 and its ligand PD-L1. LÄS MER

4. 3. Antibody Feedback Regulation and T Cells

   Författare :Fredrik Carlsson; Birgitta Heyman; Alf Grandien; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fc receptors; B cell; T cell; antigen presentation; complement receptors; complement; IgE; IgG3; CD23; antibody; Immunology; Immunologi;

   Sammanfattning : Antibodies, passively administered or actively produced, regulate immune responses to the antigen they recognize. This phenomenon is called antibody-mediated feedback regulation. Feedback regulation can be positive or negative, resulting in >1000-fold enhancement or >99% suppression of the specific antibody response. LÄS MER

5. 4. Extrathymic T cell receptor gene rearrangement in human alimentary tract

   Författare :Anna Bas; Marie-Louise Hammarström; Sten Hammarström; Adrian Hayday; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell maturation; recombination activating gene; preTα; human intestinal mucosa; intraepithelial lymphocytes; lamina propria lymphocytes; nasopharyngeal tonsil; Immunologi; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : T lymphocytes regulate the initiation, duration, and magnitude of adaptive immune responses and function as effector cells in cell mediated immunity. To become immunologically competent they must generate functional antigen receptors. This process takes place in the thymus and requires somatic recombination of T cell receptor (TCR) genes. LÄS MER

7. 5. Feedback Enhancement of Immune Responses by IgE, IgM, and IgG3 Antibodies

   Författare :Zhoujie Ding; Birgitta Heyman; Eva Severinson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgE; IgM; IgG3; antibody responses; T-cell responses; antigen transportation; antigen presentation; complement; complement receptors 1 and 2; Immunologi; Immunology;

   Sammanfattning : Antibodies can enhance or suppress the immune responses against their specific antigens. This phenomenon is known as antibody-mediated feedback regulation. We have studied the mechanisms underlying IgE-, IgM-, and IgG3-mediated enhancement of immune responses in mouse models using intravenous immunization. LÄS MER