Sökning: "oxadiazole"
Hittade 5 avhandlingar innehållade ordet oxadiazole.
1. Exploring Palladium-Mediated 11C/12C-Carbonylation Reactions : PET Tracer Development Targeting the Vesicular Acetylcholine Transporter
Sammanfattning : The work presented herein describes the utilization and exploration of palladium-mediated incorporations of carbon monoxide and/or [11C]carbon monoxide into compounds and structural motifs with biological relevance.The first part of the thesis describes the design, synthesis and 11C-labeling of prospective PET tracers for the vesicular acetylcholine transporter (VAChT), a target affected in several neurodegenerative diseases. LÄS MER
2. Design and Synthesis of Malarial Aspartic Protease Inhibitors
Sammanfattning : Malaria is one of the major public health problems in the world. Approximately 500 million people are afflicted and almost 3 million people die from the disease each year. Of the four causative species Plasmodium falciparum is the most lethal. LÄS MER
3. Prevention of intimal hyperplasia after balloon angioplasty and / or stent insertion. or How to mend a broken heart - Just say NO
Sammanfattning : Background: Restenosis is the most frequently occurring adverse event after percutaneous intravascular treatment of atherosclerotic lesions, which limits long-term patency of the intervention. Objective: The aim of the study was to evaluate if minimizing vascular injury during treatment by insertion of self-expanding stents or modifying the reparative mechanisms by local drug delivery can reduce restenosis. LÄS MER
4. Optical Modeling and Characterization of Layers and Multilayer Structures : Organic Optoelectronic Devices and Spectroscopic Ellipsometry
Sammanfattning : This dissertation is on the subject of modeling and characterization of layers and multilayer structures with respect to their optical properties and characteristics. A number of different systems have been investigated; among them multilayer structures in the form of organic optoelectronic devices, anisotropic layers of conjugated polymers as well as inhomogeneous layers of porous silicon and oxidized silver. LÄS MER
5. Luminescent Polymer Films in Layered Devices : A Theoretical and Experimental Study on Light Emission from Polymer-based Devices
Sammanfattning : This thesis concerns optical modelling and characterisation of thin film layered structures, including luminescent conjugated polymers, with respect to the emission properties. Included in the study were three different types of devices: Organic light-emitting diodes, microcavities and half cavities. LÄS MER