Sökning: "oligodendrocyte"

Visar resultat 26 - 30 av 59 avhandlingar innehållade ordet oligodendrocyte.

  1. 26. Novel Immunotherapies and Immunoregulation in a Chronic Inflammatory Disease of the Central Nervous System

    Författare :Shahram Lavasani; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; Djurfysiologi; Animal physiology; probiotics; immunotherapy; CD1; T-cell; CNS; inflammation; EAE; MS; neuropsykologi; neurofysiologi;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system (CNS) which is thought to arise from a breakdown of immunological tolerance in CD4 cells. The aim of this thesis is to improve our understanding of regulation mechanisms of T cell-dependent chronic inflammation in the CNS and explore ways to overcome the onset and progression of the disease, which can be an important step forward in the treatment of MS. LÄS MER

  3. 27. Expression of sulfatide in rodent CNS - not only restricted to myelin

    Författare :Zarah Pernber; Göteborgs universitet; []
    Nyckelord :sulfatide; glycosphingolipid; neurons; astrocytes; immunohistochemistry; brain; metachromatic leukodystrophy;

    Sammanfattning : Sulfatide is an acidic glycosphingolipid and a component of myelin in the nervous system proposed to be involved in maintenance of the myelin structure and thereby its function. Sulfatide is also a commonly used marker for detection of oligodendrocyte progenitor cells in cultures as well as in tissues. LÄS MER

  4. 28. Inheritance of autoimmune neuroinflammation

    Författare :Pernilla Stridh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic neuro-inflammatory disease with anticipated complex etiology. Susceptibility to MS is conferred by numerous genes, with very low odds ratios that explain minute fractions of disease. This indicates that unknown factors are responsible for the remaining genetic contribution, termed the missing heritability. LÄS MER

  5. 29. Genetic dissection of experimental autoimmune neuroinflammatory diseases in rats

    Författare :Ingrid Dahlman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple Sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system (CNS) causing neurological deficits. The disease has a complex etiology comprising multiple unidentified susceptibility genes and environmental influences. LÄS MER

  7. 30. Neurogenesis, neural stem cells and nitric oxide in neuroinflammation

    Författare :Alexandre I Danilov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neurogenesis; neuronal stem cells; nitric oxide; Multiple Sclerosis; EAE; brain trauma;

    Sammanfattning : We investigated whether nitric oxide (NO) is produced in MS patients, determining the concentrations of its oxidation products (NOx) in CSF. The total levels of NOx in CSF were significantly increased in all MS groups as compared to healthy controls and tension headache patients. LÄS MER