Sökning: "oligodendrocyte"

Visar resultat 16 - 20 av 59 avhandlingar innehållade ordet oligodendrocyte.

  1. 16. An ependymal cell quest : identification and functional role of spinal cord neural stem cells

    Författare :Hanna Sabelström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Few injuries have as profound and long-lasting consequences as spinal cord injury. The primary areas of impaired function typically include sensation, mobility, bladder, bowel and sexual function. The economic, social and personal effects can also be devastating. LÄS MER

  3. 17. Molecular determinants of endocannabinoid-mediated brain development

    Författare :Daniela Calvigioni; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The enchanting process of brain development entails a fragile and finite time window, throughout which biochemical imbalances and external insults can potentially affect developing neuronal circuits. Within the numerous exquisitely orchestrated events taking place in the foetal brain, axonal pathfinding is of paramount importance. LÄS MER

  4. 18. Immune regulation within the central nervous system and its role in demyelinating diseases

    Författare :Bao-Guo Xiao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) and its animal model, experimental allergic encephalomyelitis (EAE), are diseases of the central nervous system (CNS) characterized by perivascular mononuclear inflammation and oligodendrocyte loss with demyelination. However, it is still not clear whether the pathology in MS and EAE is due to neuroantigen-specific CD4+ T cell-mediated autoimmune responses and/or bystander myelin damage resulting from an inflammatory response. LÄS MER

  5. 19. A study of the generation of diversity in the central nervous system

    Författare :Joanna Applequist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Developmental biology is concerned with understanding the mechanisms that govern the generation of a whole organism starting from one single cell. In the central nervous system (CNS) the development of different classes of neurons and glial cells involves both extrinsic signals and intrinsic cues that together govern the specification of different cell fates dependent on position within the CNS and the time of generation. LÄS MER

  7. 20. Inhibition of T cell responses to autoantigens and allergens by CD25+ regulatory T cells from thymus, cord and adult blood

    Författare :Kajsa Wing; Göteborgs universitet; []
    Nyckelord :Tolerance; CD25 regulatory T cells; adult peripheral blood; cord blood; thymus; autoimmune disease; allergy;

    Sammanfattning : Autoimmune diseases and allergies are a growing problem in the western world today. Tolerance is primarily established by clonal deletion in the thymus. Despite this auto-reactive T cells are normally present in most individuals, which suggests that mechanisms of peripheral tolerance operate to silence potentially pathogenic T cells. LÄS MER