Sökning: "metachromatic leukodystrophy"

Hittade 2 avhandlingar innehållade orden metachromatic leukodystrophy.

1. 1. Expression of sulfatide in rodent CNS - not only restricted to myelin

   Författare :Zarah Pernber; Göteborgs universitet; []
   Nyckelord :sulfatide; glycosphingolipid; neurons; astrocytes; immunohistochemistry; brain; metachromatic leukodystrophy;

   Sammanfattning : Sulfatide is an acidic glycosphingolipid and a component of myelin in the nervous system proposed to be involved in maintenance of the myelin structure and thereby its function. Sulfatide is also a commonly used marker for detection of oligodendrocyte progenitor cells in cultures as well as in tissues. LÄS MER

3. 2. Development of Enhanced Analytical Methodology for Lipid Analysis from Sampling to Detection : A Targeted Lipidomics Approach

   Författare :Giorgis Isaac; Jonas Bergquist; Karin Markides; Monica Waldebäck; William Christie; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; electrospray ionization; lipids; liquid chromatography; mass spectrometry; pesticides; phosphatidylcholine; pressurized fluid extraction; sphingomyelin; sulfatides; Analytisk kemi; Analytical chemistry; Analytisk kemi;

   Sammanfattning : This thesis covers a wide range of analytical method development for lipid analysis in complex biological samples; from sample preparation using pressurized fluid extraction (PFE) and separation with reversed phase capillary liquid chromatography (RP-LC) to detection by electrospray ionization mass spectrometry (ESI/MS) and tandem MS.The requirements for fast, reliable and selective extraction methods with minimal usage of solvents have accelerated the development of new extraction techniques. LÄS MER