Sökning: "oligodendrocyte"
Visar resultat 11 - 15 av 59 avhandlingar innehållade ordet oligodendrocyte.
11. Immunogenetics and treatment of experimental autoimmune encephalomyelitis
Sammanfattning : Experimental autoimmune encephalomyelities (EAE) is a model of multiple sclerosis (MS). This experimental central nervous system (CNS) disease can be induced in rats by immunization with components of the CNS myelin sheath. LÄS MER
12. Suppressive DNA vaccination in experimental autoimmune encephalomyelitis
Sammanfattning : This thesis describes the development of a novel method to suppress an organ-specific autoimmune disease, experimental autoimmune encephalomyelitis (EAE), by vaccination with DNA encoding autoantigenic peptides. DNA vaccination can produce long-term immunity and generate antigen-specific CD8+ and CD4+ T cells. LÄS MER
13. Brain matter matters : renewal in the human brain
Sammanfattning : Many cells have a shorter life span than the organism itself and are continuously being replaced. However, for many cell types in the human body it is still largely unknown whether they turn over at all once development is complete. LÄS MER
14. On molecular mechanisms of neural differentiation and forebrain development
Sammanfattning : Telencephalic development is an extraordinary complex process where neural structures of highly diverse cell compositions emerge as the result of multiple developmental strategies imposing tight regulation, balance and timing of gene expression. Embryonic telencephalic neural stem cells (NSCs) can form the major cell types found in the telencephalon, and are thus an excellent model for studying transcriptional control of lineage choice mechanisms in CNS development. LÄS MER
15. Stem cell-based models to study cellular alterations in Parkinson’s Disease
Sammanfattning : Parkinson’s Disease (PD) is the most prevalent neurodegenerative movement disorder. Despite investigative efforts into the pathogenesis of the disease, the aetiology and mechanism of PD remains unknown, with multiple factors and cellular pathways known to play a part. LÄS MER