Sökning: "oligodendrocyte"

Visar resultat 31 - 35 av 59 avhandlingar innehållade ordet oligodendrocyte.

  1. 31. Chemokine receptor expression and function in experimental autoimmune neuroinflammation

    Författare :Sana Eltayeb; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neuroinflammatory lesions in the central nervous system (CNS) are characterized by the presence of leukocytes, mainly monocytes/macrophages, derived from the systemic compartment. We believe CC inflammatory chemokine receptors (CkRs), CCR1, CCR2 and CCR5 are prerequisite for controlling the migration of monocytes/macrophages into inflammatory foci. LÄS MER

  3. 32. Genetic regulation of autoimmunity in experimental neuroinflammation

    Författare :Sevasti Flytzani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system causing axonal demyelination and leads to significant disabilities. MS affects mainly young adults and incidence of disease in Sweden is around 600 new cases/year. LÄS MER

  4. 33. Functions of platelet-derived growth factor-A during organogenesis

    Författare :Linda Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet-derived growth factor-A; knockout; mouse organogenesis; epithelial-mesenchymalinteractions; skin; hair follicles; CNS; lung; gastrointestinal villus;

    Sammanfattning : The formation of organs during embryonic development is calledorganogenesis. This process is regulated by the genes residing in the genome. LÄS MER

  5. 34. The release of histone proteins from cells via extracellular vesicles

    Författare :Uma Muthukrishnan; Jonathan Gilthorpe; Miles Trupp; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone; extracellular vesicles; exosomes; extracellular histones extracellular DNA; cellular stress; proteomics; ESCRT complex; Lrrn1; mid-hindbrain organizer; ovarian cancer; ascites;

    Sammanfattning : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. LÄS MER

  7. 35. Genetic regulation of neuroinflammation : a translational approach

    Författare :Johan Öckinger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), causing demyelination and axonal damage. As other complex diseases with an inflammatory or autoimmune component, MHC is a strong regulator of the disease and acts in concert with multiple nonMHC genes and environmental factors. LÄS MER