Sökning: "myeloid dendritic cells"

Visar resultat 11 - 15 av 50 avhandlingar innehållade orden myeloid dendritic cells.

1. 11. Human myeloid cells in cancer, inflammation, and infection

   Författare :Eglė Kvedaraitė; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Myeloid cells are a part of innate immunity, playing a major role in orchestrating innate and adaptive immune responses. While work performed in experiment model systems has significantly increased our knowledge on fundamental myeloid cell functions, studies in well-designed clinical cohorts are important for understanding their functions in human health and disease, such as in cancer, infection and chronic inflammation. LÄS MER

3. 12. Immunosuppressive Myeloid Cells in Breast Cancer and Sepsis

   Författare :Caroline Bergenfelz; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Immune cells play paradoxical roles in cancer progression. On one hand, the immune system protects us against tumor development by recognizing and eliminating cancerous cells. LÄS MER

4. 13. On the role of dendritic cells in HIV-1 infection

   Författare :Anna Smed Sörensen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Dendritic cell; plasmacytoid; myeloid; HIV-1; cytokines; co-stimulation; transmission; antigen presentation; apoptotic cells; MuLV;

   Sammanfattning : Dendritic cells (DCs) are antigen-presenting cells with the capacity to initiate primary T cell responses against pathogens such as HIV-1. In addition, DCs express the receptors required for HIV-1 infection and as DCs are prevalent in the mucosa, they encounter the virus early after sexual transmission. LÄS MER

5. 14. Redox reactions in cancer: impact and regulation

   Författare :Hanna Grauers Wiktorin; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Immunotherapy; reactive oxygen species; NOX2; histamine dihydrochloride; myeloid-derived suppressor cells; checkpoint inhibition; acute myeloid leukemia; chronic myeloid leukemia;

   Sammanfattning : The reduction-oxidation (redox) reaction involves a change in the oxidation state of molecules where a molecule that donates an electron is oxidized and a molecule that accepts an electron is reduced. The NADPH oxidase of myeloid cells, NOX2, is a major source of oxidants in the form of reactive oxygen species (ROS), which are short-lived oxygen derivatives. LÄS MER

7. 15. Human cytomegalovirus and dendritic cell interaction : role in immunosupression and autoimmunity

   Författare :Stefania Varani; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cytomegalovirus; myeloid dendritic cells; plasmacytoid dendritic cells; immunosuppression; autoimmunity.;

   Sammanfattning : Human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality in patients with an impaired immune system. The virus itself can cause transitory but significant immunosuppression in immunocompetent as well as immunocompromised infected individuals. LÄS MER